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The signaling axis atypical protein kinase C λ/ι-Satb2 mediates leukemic transformation of B-cell progenitors

Epigenetically regulated transcriptional plasticity has been proposed as a mechanism of differentiation arrest and resistance to therapy. BCR-ABL leukemias result from leukemic stem cell/progenitor transformation and represent an opportunity to identify epigenetic progress contributing to lineage le...

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Detalles Bibliográficos
Autores principales:	Nayak, R. C., Hegde, S., Althoff, M. J., Wellendorf, A. M., Mohmoud, F., Perentesis, J., Reina-Campos, M., Reynaud, D., Zheng, Y., Diaz-Meco, M. T., Moscat, J., Cancelas, J. A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6320370/ https://www.ncbi.nlm.nih.gov/pubmed/30610188 http://dx.doi.org/10.1038/s41467-018-07846-y

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