The Japanese Early-Stage Trial of High-Dose Methylcobalamin for Amyotrophic Lateral Sclerosis (JETALS): Protocol for a Randomized Controlled Trial

BACKGROUND: Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease that affects the upper and lower motor neurons. Currently, only riluzole and edaravone are approved as drugs to treat ALS and new agents with larger effect sizes are warranted. Exploratory analyses in our previous study (...

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Detalles Bibliográficos
Autores principales: Oki, Ryosuke, Izumi, Yuishin, Nodera, Hiroyuki, Sato, Yasutaka, Nokihara, Hiroshi, Kanai, Kazuaki, Sonoo, Masahiro, Urushitani, Makoto, Nishinaka, Kazuto, Atsuta, Naoki, Kohara, Nobuo, Shimizu, Toshio, Kikuchi, Hitoshi, Oda, Masaya, Ikeda, Ken, Nagai, Makiko, Komai, Kiyonobu, Kojima, Yasuhiro, Kuzume, Daisuke, Isose, Sagiri, Shimohama, Shun, Abe, Koji, Ito, Hidefumi, Noda, Kazuyuki, Ishihara, Tomohiko, Morita, Mitsuya, Shimohata, Takayoshi, Teramukai, Satoshi, Kagimura, Tatsuo, Noma, Kensuke, Yanagawa, Hiroaki, Kuwabara, Satoshi, Kaji, Ryuji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: JMIR Publications 2018
Materias:
Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6320396/
https://www.ncbi.nlm.nih.gov/pubmed/30578206
http://dx.doi.org/10.2196/12046

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