Cargando…

Severe Thrombocytopenia in Patient with Dermatomyositis

ABSTRACT: Dermatomyositis (DM) is part of a heterogeneous group of systemic diseases called idiopathic inflammatory myopathies. As in other autoimmune connective tissue diseases (CTD), abnormalities of hematopoietic tissue and/or peripheral blood cells may develop and represent an important prognost...

Descripción completa

Detalles Bibliográficos
Autores principales: TUDORANCEA, A.D., CIUREA, P.L., VREJU, F.A., VINTILA, E.M., DINESCU, Ș.C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medical University Publishing House Craiova 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6320470/
https://www.ncbi.nlm.nih.gov/pubmed/30687531
http://dx.doi.org/10.12865/CHSJ.44.02.17
Descripción
Sumario:ABSTRACT: Dermatomyositis (DM) is part of a heterogeneous group of systemic diseases called idiopathic inflammatory myopathies. As in other autoimmune connective tissue diseases (CTD), abnormalities of hematopoietic tissue and/or peripheral blood cells may develop and represent an important prognostic factor. Most common CTD associated with thrombocytopenia (TP) are systemic lupus erythematosus and antiphospholipid syndrome. DM-related TP is less frequent and may develop in the context of an underlying malignancy. Severe TP related to myositis is a very rare occurrence. We report a case of a male patient diagnosed with acute DM, debilitating muscle weakness and rapid development of severe TP.