Human induced pluripotent stem cell-derived MGE cell grafting after status epilepticus attenuates chronic epilepsy and comorbidities via synaptic integration

Medial ganglionic eminence (MGE)-like interneuron precursors derived from human induced pluripotent stem cells (hiPSCs) are ideal for developing patient-specific cell therapy in temporal lobe epilepsy (TLE). However, their efficacy for alleviating spontaneous recurrent seizures (SRS) or cognitive, m...

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Detalles Bibliográficos
Autores principales: Upadhya, Dinesh, Hattiangady, Bharathi, Castro, Olagide W., Shuai, Bing, Kodali, Maheedhar, Attaluri, Sahithi, Bates, Adrian, Dong, Yi, Zhang, Su-Chun, Prockop, Darwin J., Shetty, Ashok K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2019
Materias:
PNAS Plus
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6320542/
https://www.ncbi.nlm.nih.gov/pubmed/30559206
http://dx.doi.org/10.1073/pnas.1814185115

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6320542/
https://www.ncbi.nlm.nih.gov/pubmed/30559206
http://dx.doi.org/10.1073/pnas.1814185115

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