Cargando…

Glutamine protects against oxidative stress injury through inhibiting the activation of PI3K/Akt signaling pathway in parkinsonian cell model

BACKGROUND: Parkinson’s disease is a neurodegenerative disorder, and recent studies suggested that oxidative stress contributes to the degeneration of dopamine cell in Parkinson’s disease. Glutamine also has a positive role in reducing oxidative stress damage. In this study, we hypothesized that glu...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhao, Yingqian, Wang, Qiang, Wang, Yuan, Li, Jie, Lu, Gang, Liu, Zhibin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6320634/ https://www.ncbi.nlm.nih.gov/pubmed/30611190 http://dx.doi.org/10.1186/s12199-018-0757-5

Ejemplares similares

Effect of PI3K/Akt/mTOR signaling pathway on JNK3 in Parkinsonian rats
por: Chen, Ying, et al.
Publicado: (2019)

Oligo-Porphyran Ameliorates Neurobehavioral Deficits in Parkinsonian Mice by Regulating the PI3K/Akt/Bcl-2 Pathway
por: Liu, Yingjuan, et al.
Publicado: (2018)

BRD4 Inhibition Protects Against Myocardial Ischemia/Reperfusion Injury by Suppressing Inflammation and Oxidative Stress Through the PI3K/AKT Signaling Pathway
por: Wei, Hongwei, et al.
Publicado: (2021)

Glutamine relieves oxidative stress through PI3K/Akt signaling pathway in DSS-induced ulcerative colitis mice
por: Yan, Shuguang, et al.
Publicado: (2020)

Glutamine Improves Oxidative Stress through the Wnt3a/β-Catenin Signaling Pathway in Alzheimer's Disease In Vitro and In Vivo
por: Wang, Yuan, et al.
Publicado: (2019)

ELA-11 protects the heart against oxidative stress injury induced apoptosis through ERK/MAPK and PI3K/AKT signaling pathways
por: Wang, Xuejun, et al.
Publicado: (2022)

Hydroxytyrosol Protects against Myocardial Ischemia/Reperfusion Injury through a PI3K/Akt-Dependent Mechanism
por: Pei, Ying-hao, et al.
Publicado: (2016)

Hederagenin Protects PC12 Cells Against Corticosterone-Induced Injury by the Activation of the PI3K/AKT Pathway
por: Lin, Ruohong, et al.
Publicado: (2021)

Piperine protects against myocardial ischemia/reperfusion injury by activating the PI3K/AKT signaling pathway
por: Li, Yun-Peng, et al.
Publicado: (2021)

(−)-Epicatechin protects against myocardial ischemia-induced cardiac injury via activation of the PTEN/PI3K/AKT pathway
por: Li, Jia-Wen, et al.
Publicado: (2018)

Benazepril hydrochloride protects against doxorubicin cardiotoxicity by regulating the PI3K/Akt pathway
por: Zhan, Lan, et al.
Publicado: (2021)

Atractylenolide III Ameliorates Bile Duct Ligation-Induced Liver Fibrosis by Inhibiting the PI3K/AKT Pathway and Regulating Glutamine Metabolism
por: Wang, Yan, et al.
Publicado: (2023)

Sulfiredoxin-1 protects against simulated ischaemia/reperfusion injury in cardiomyocyte by inhibiting PI3K/AKT-regulated mitochondrial apoptotic pathways
por: Zhang, Jiankai, et al.
Publicado: (2016)

The protective effects of shikonin on hepatic ischemia/reperfusion injury are mediated by the activation of the PI3K/Akt pathway
por: Liu, Tong, et al.
Publicado: (2017)

Erzhi Pill(®) Protected Experimental Liver Injury Against Apoptosis via the PI3K/Akt/Raptor/Rictor Pathway
por: Zhao, Hai-Mei, et al.
Publicado: (2018)

Baicalein Protects Rats with Diabetic Cardiomyopathy Against Oxidative Stress and Inflammation Injury via Phosphatidylinositol 3-Kinase (PI3K)/AKT Pathway
por: Ma, Lin, et al.
Publicado: (2018)

Kaempferide Protects against Myocardial Ischemia/Reperfusion Injury through Activation of the PI3K/Akt/GSK-3β Pathway
por: Wang, Dong, et al.
Publicado: (2017)

Penehyclidine hydrochloride protects against lipopolysaccharide-induced acute lung injury by promoting the PI3K/Akt pathway
por: Weng, Junting, et al.
Publicado: (2023)

The Antagonistic Effect of Glutamine on Zearalenone-Induced Apoptosis via PI3K/Akt Signaling Pathway in IPEC-J2 Cells
por: Wang, Tianhu, et al.
Publicado: (2021)

Alpha-Linolenic Acid Exerts an Endothelial Protective Effect against High Glucose Injury via PI3K/Akt Pathway
por: Zhang, Wei, et al.
Publicado: (2013)

K-3-Rh Protects Against Cerebral Ischemia/Reperfusion Injury by Anti-Apoptotic Effect Through PI3K-Akt Signaling Pathway in Rat
por: Sun, Juan, et al.
Publicado: (2020)

Arginine, N-carbamylglutamate, and glutamine exert protective effects against oxidative stress in rat intestine
por: Xiao, Liang, et al.
Publicado: (2016)

Myricetin Protects Cells against Oxidative Stress-Induced Apoptosis via Regulation of PI3K/Akt and MAPK Signaling Pathways
por: Kang, Kyoung Ah, et al.
Publicado: (2010)

Tanshinone IIA protects mice against atherosclerotic injury by activating the TGF-β/PI3K/Akt/eNOS pathway
por: Wang, Junyan, et al.
Publicado: (2020)

Inhibition of autophagy via activation of PI3K/Akt/mTOR pathway contributes to the protection of hesperidin against myocardial ischemia/reperfusion injury
por: Li, Xuefei, et al.
Publicado: (2018)

Gualou Guizhi Granule Protects against OGD/R-Induced Injury by Inhibiting Cell Pyroptosis via the PI3K/Akt Signaling Pathway
por: Zhang, Yuqin, et al.
Publicado: (2021)

Dexmedetomidine Protects Against Lipopolysaccharide-Induced Acute Kidney Injury by Enhancing Autophagy Through Inhibition of the PI3K/AKT/mTOR Pathway
por: Zhao, Yuan, et al.
Publicado: (2020)

The Treadmill Exercise Protects against Dopaminergic Neuron Loss and Brain Oxidative Stress in Parkinsonian Rats
por: da Costa, Roberta Oliveira, et al.
Publicado: (2017)

HMGB1 Protects the Heart Against Ischemia–Reperfusion Injury via PI3K/AkT Pathway-Mediated Upregulation of VEGF Expression
por: Zhou, Yan-Hong, et al.
Publicado: (2020)

Genistein Protects Genioglossus Myoblast Against Hypoxia-induced Injury through PI3K-Akt and ERK MAPK Pathways
por: Ding, Wanghui, et al.
Publicado: (2017)

Aloperine protects against cerebral ischemia/reperfusion injury via activating the PI3K/AKT signaling pathway in rats
por: Li, Zhimin, et al.
Publicado: (2021)

1,2,3,4,6-O-Pentagalloylglucose Protects against Acute Lung Injury by Activating the AMPK/PI3K/Akt/Nrf2 Pathway
por: Zhang, Qi, et al.
Publicado: (2022)

Modulation of telomere protection by the PI3K/AKT pathway
por: Méndez-Pertuz, Marinela, et al.
Publicado: (2017)

Piceatannol Protects Human Retinal Pigment Epithelial Cells against Hydrogen Peroxide Induced Oxidative Stress and Apoptosis through Modulating PI3K/Akt Signaling Pathway
por: Hao, Yiming, et al.
Publicado: (2019)

Screening of PI3K-Akt-targeting Drugs for Silkworm against Bombyx mori Nucleopolyhedrovirus
por: Wang, Bingbing, et al.
Publicado: (2019)

PI3K/Akt Pathway Contributes to Neurovascular Unit Protection of Xiao-Xu-Ming Decoction against Focal Cerebral Ischemia and Reperfusion Injury in Rats
por: Lan, Rui, et al.
Publicado: (2013)

Sevoflurane Postconditioning Protects Rat Hearts against Ischemia-Reperfusion Injury via the Activation of PI3K/AKT/mTOR Signaling
por: Zhang, Jing, et al.
Publicado: (2014)

Mild hypothermia pretreatment protects against liver ischemia reperfusion injury via the PI3K/AKT/FOXO3a pathway
por: Xiao, Qi, et al.
Publicado: (2017)

Vinpocetine Protects Against Cerebral Ischemia-Reperfusion Injury by Targeting Astrocytic Connexin43 via the PI3K/AKT Signaling Pathway
por: Zhao, Mingming, et al.
Publicado: (2020)

Protective Effect Of Vasicine Against Myocardial Infarction In Rats Via Modulation Of Oxidative Stress, Inflammation, And The PI3K/Akt Pathway
por: Jiang, Tiechao, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_1k1nn0pmi0ak3o7vh2p1s9gfqi