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Adults with septic shock and extreme hyperferritinemia exhibit pathogenic immune variation
Post-hoc subgroup analysis of the negative trial of interleukin-1β receptor antagonist (IL1RA) for septic shock suggested that patients with features of macrophage activation syndrome (MAS) experienced a 50% relative risk reduction for mortality with treatment. Here we seek a genetic basis for this...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6320733/ https://www.ncbi.nlm.nih.gov/pubmed/29977033 http://dx.doi.org/10.1038/s41435-018-0030-3 |