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Time resolved quantitative phospho-tyrosine analysis reveals Bruton’s Tyrosine kinase mediated signaling downstream of the mutated granulocyte-colony stimulating factor receptors

Granulocyte-colony stimulating factor receptor (G-CSFR) controls myeloid progenitor proliferation and differentiation to neutrophils. Mutations in CSF3R (encoding G-CSFR) have been reported in patients with chronic neutrophilic leukemia (CNL) and acute myeloid leukemia (AML); however, despite years...

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Detalles Bibliográficos
Autores principales:	Dwivedi, Pankaj, Muench, David E., Wagner, Michael, Azam, Mohammad, Grimes, H. Leighton, Greis, Kenneth D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6320735/ https://www.ncbi.nlm.nih.gov/pubmed/29977015 http://dx.doi.org/10.1038/s41375-018-0188-8

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