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Intracellular Accumulation of Linezolid and Florfenicol in OptrA-Producing Enterococcus faecalis and Staphylococcus aureus

The optrA gene, which confers transferable resistance to oxazolidinones and phenicols, is defined as an ATP-binding cassette (ABC) transporter but lacks transmembrane domains. The resistance mechanism of optrA and whether it involves antibiotic efflux or ribosomal protection remain unclear. In this...

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Detalles Bibliográficos
Autores principales:	Wang, Yingyu, Li, Xiaowei, Wang, Yang, Schwarz, Stefan, Shen, Jianzhong, Xia, Xi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6320770/ https://www.ncbi.nlm.nih.gov/pubmed/30518106 http://dx.doi.org/10.3390/molecules23123195

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