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The Influence of Polymers on the Supersaturation Potential of Poor and Good Glass Formers
The increasing number of poorly water-soluble drug candidates in pharmaceutical development is a major challenge. Enabling techniques such as amorphization of the crystalline drug can result in supersaturation with respect to the thermodynamically most stable form of the drug, thereby possibly incre...
Autores principales: | Blaabjerg, Lasse I., Grohganz, Holger, Lindenberg, Eleanor, Löbmann, Korbinian, Müllertz, Anette, Rades, Thomas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6320775/ https://www.ncbi.nlm.nih.gov/pubmed/30241425 http://dx.doi.org/10.3390/pharmaceutics10040164 |
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