Strategies to Obtain Encapsulation and Controlled Release of Pentamidine in Mesoporous Silica Nanoparticles

Pentamidine (PTM), an antiprotozoal agent used in clinics as pentamidine isethionate salt (PTM-S), recently showed high potential also for the treatment of cancer and myotonic dystrophy type I. However, a severe limit to the systemic administration of PTM is represented by its nephrotoxicity, leadin...

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Detalles Bibliográficos
Autores principales: Peretti, Enrico, Miletto, Ivana, Stella, Barbara, Rocco, Flavio, Berlier, Gloria, Arpicco, Silvia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6320796/
https://www.ncbi.nlm.nih.gov/pubmed/30347763
http://dx.doi.org/10.3390/pharmaceutics10040195

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