The Xanthine Oxidase Inhibitor Febuxostat Suppresses the Progression of IgA Nephropathy, Possibly via Its Anti-Inflammatory and Anti-Fibrotic Effects in the gddY Mouse Model

Recent clinical studies have demonstrated the protective effect of xanthine oxidase (XO) inhibitors against chronic kidney diseases, although the underlying molecular mechanisms remain unclear. However, to date, neither clinical nor basic research has been carried out to elucidate the efficacy of XO...

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Detalles Bibliográficos
Autores principales: Inoue, Masa-Ki, Yamamotoya, Takeshi, Nakatsu, Yusuke, Ueda, Koji, Inoue, Yuki, Matsunaga, Yasuka, Sakoda, Hideyuki, Fujishiro, Midori, Ono, Hiraku, Morii, Kenichi, Sasaki, Kensuke, Masaki, Takao, Suzuki, Yusuke, Asano, Tomoichiro, Kushiyama, Akifumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6320819/
https://www.ncbi.nlm.nih.gov/pubmed/30544662
http://dx.doi.org/10.3390/ijms19123967

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6320819/
https://www.ncbi.nlm.nih.gov/pubmed/30544662
http://dx.doi.org/10.3390/ijms19123967

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