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In Vitro Immune Organs-on-Chip for Drug Development: A Review

The current drug development practice lacks reliable and sensitive techniques to evaluate the immunotoxicity of drug candidates, i.e., their effect on the human immune system. This, in part, has resulted in a high attrition rate for novel drugs candidates. Organ-on-chip devices have emerged as key t...

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Detalles Bibliográficos
Autores principales: Shanti, Aya, Teo, Jeremy, Stefanini, Cesare
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6320867/
https://www.ncbi.nlm.nih.gov/pubmed/30558264
http://dx.doi.org/10.3390/pharmaceutics10040278