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Discovery of a Natural Syk Inhibitor from Chinese Medicine through a Docking-Based Virtual Screening and Biological Assay Study

Spleen tyrosine kinase (Syk) is a critical target protein for treating immunoreceptor signalling-mediated allergies. In this study, a virtual screening of an in-house Chinese medicine database followed by biological assays was carried out to identify novel Syk inhibitors. A molecular docking method...

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Detalles Bibliográficos
Autores principales:	Wang, Xing, Guo, Junfang, Ning, Zhongqi, Wu, Xia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6320911/ https://www.ncbi.nlm.nih.gov/pubmed/30487406 http://dx.doi.org/10.3390/molecules23123114

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