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Biodistribution of a Radiolabeled Antibody in Mice as an Approach to Evaluating Antibody Pharmacokinetics

(1) Background: Monoclonal antibodies are used in the treatment of multiple conditions including cancer, autoimmune disorders, and infectious diseases. One of the initial steps in the selection of an antibody candidate for further pre-clinical development is determining its pharmacokinetics in small...

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Detalles Bibliográficos
Autores principales:	Allen, Kevin J. H., Jiao, Rubin, Malo, Mackenzie E., Frank, Connor, Dadachova, Ekaterina
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2018
Materias:	Communication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6320949/ https://www.ncbi.nlm.nih.gov/pubmed/30563123 http://dx.doi.org/10.3390/pharmaceutics10040262

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