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Intracerebral Delivery of Brain-Derived Neurotrophic Factor Using HyStem(®)-C Hydrogel Implants Improves Functional Recovery and Reduces Neuroinflammation in a Rat Model of Ischemic Stroke
Ischemic stroke is a leading cause of death and disability worldwide. Potential therapeutics aimed at neural repair and functional recovery are limited in their blood-brain barrier permeability and may exert systemic or off-target effects. We examined the effects of brain-derived neurotrophic factor...
Autores principales: | Ravina, Kristine, Briggs, Denise I., Kislal, Sezen, Warraich, Zuha, Nguyen, Tiffany, Lam, Rachel K., Zarembinski, Thomas I., Shamloo, Mehrdad |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6321015/ https://www.ncbi.nlm.nih.gov/pubmed/30486515 http://dx.doi.org/10.3390/ijms19123782 |
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