Synthesis and Characterization of a Biomimetic Formulation of Clofazimine Hydrochloride Microcrystals for Parenteral Administration

Clofazimine (CFZ) is a broad spectrum antimycobacterial agent recommended by the World Health Organization as a first line treatment for leprosy and second line treatment for multidrug resistant tuberculosis. Oral administration of CFZ leads to a red skin pigmentation side effect. Since CFZ is a wea...

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Detalles Bibliográficos
Autores principales: Murashov, Mikhail D., Diaz-Espinosa, Jennifer, LaLone, Vernon, Tan, Joel W. Y., Laza, Raluca, Wang, Xueding, Stringer, Kathleen A., Rosania, Gus R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6321048/
https://www.ncbi.nlm.nih.gov/pubmed/30453628
http://dx.doi.org/10.3390/pharmaceutics10040238

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