Glucocorticoid Receptor Binding Inhibits an Intronic IL33 Enhancer and is Disrupted by rs4742170 (T) Allele Associated with Specific Wheezing Phenotype in Early Childhood

Interleukin 33 (IL-33) is a cytokine constitutively expressed by various cells of barrier tissues that contribute to the development of inflammatory immune responses. According to its function as an alarmin secreted by lung and airway epithelium, IL-33 plays a significant role in pathogenesis of all...

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Detalles Bibliográficos
Autores principales: Gorbacheva, Alisa M., Kuprash, Dmitry V., Mitkin, Nikita A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6321062/
https://www.ncbi.nlm.nih.gov/pubmed/30544846
http://dx.doi.org/10.3390/ijms19123956

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6321062/
https://www.ncbi.nlm.nih.gov/pubmed/30544846
http://dx.doi.org/10.3390/ijms19123956

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