Cargando…

Regulation of Protein Structural Changes by Incorporation of a Small-Molecule Linker

Proteins have the potential to serve as nanomachines with well-controlled structural movements, and artificial control of their conformational changes is highly desirable for successful applications exploiting their dynamic structural characteristics. Here, we demonstrate an experimental approach fo...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kim, Youngmin, Yang, Cheolhee, Kim, Tae Wu, Thamilselvan, Kamatchi, Kim, Yonggwan, Ihee, Hyotcherl
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6321067/ https://www.ncbi.nlm.nih.gov/pubmed/30469528 http://dx.doi.org/10.3390/ijms19123714

Ejemplares similares

Reversible molecular motional switch based on circular photoactive protein oligomers exhibits unexpected photo-induced contraction
por: Lee, Sang Jin, et al.
Publicado: (2021)

High-throughput instant quantification of protein expression and purity based on photoactive yellow protein turn off/on label
por: Kim, Youngmin, et al.
Publicado: (2013)

Conformational Substates of Myoglobin Intermediate Resolved by Picosecond X-ray Solution Scattering
por: Oang, Key Young, et al.
Publicado: (2014)

Cooperative protein structural dynamics of homodimeric hemoglobin linked to water cluster at subunit interface revealed by time-resolved X-ray solution scattering
por: Kim, Jong Goo, et al.
Publicado: (2016)

SVD-aided pseudo principal-component analysis: A new method to speed up and improve determination of the optimum kinetic model from time-resolved data
por: Oang, Key Young, et al.
Publicado: (2017)

Measurements of complex refractive index change of photoactive yellow protein over a wide wavelength range using hyperspectral quantitative phase imaging
por: Lee, KyeoReh, et al.
Publicado: (2018)

Protein Structural Dynamics of Wild-Type and Mutant Homodimeric Hemoglobin Studied by Time-Resolved X-Ray Solution Scattering
por: Yang, Cheolhee, et al.
Publicado: (2018)

Light-induced protein structural dynamics in bacteriophytochrome revealed by time-resolved x-ray solution scattering
por: Lee, Sang Jin, et al.
Publicado: (2022)

Topical Review: Molecular reaction and solvation visualized by time-resolved X-ray solution scattering: Structure, dynamics, and their solvent dependence
por: Hwan Kim, Kyung, et al.
Publicado: (2014)

Effect of the abolition of intersubunit salt bridges on allosteric protein structural dynamics
por: Choi, Minseo, et al.
Publicado: (2021)

Direct Observation of Cooperative Protein Structural Dynamics of Homodimeric Hemoglobin from 100 ps to 10 ms with Pump–Probe X-ray Solution Scattering
por: Kim, Kyung Hwan, et al.
Publicado: (2012)

Ultrafast structural dynamics of in-cage isomerization of diiodomethane in solution
por: Kim, Hanui, et al.
Publicado: (2020)

A Photoresponsive Smart Covalent Organic Framework**
por: Huang, Ning, et al.
Publicado: (2015)

Estimating signal and noise of time-resolved X-ray solution scattering data at synchrotrons and XFELs
por: Kim, Jungmin, et al.
Publicado: (2020)

Small Molecule NF-κB Pathway Inhibitors in Clinic
por: Ramadass, Venkataramanan, et al.
Publicado: (2020)

Visualizing Heterogeneous Protein Conformations with Multi-Tilt Nanoparticle-Aided Cryo-Electron Microscopy Sampling
por: Kim, Changin, et al.
Publicado: (2023)

Volume-conserving trans-cis isomerization pathways in photoactive yellow protein visualized by picosecond X-ray crystallography
por: Jung, Yang Ouk, et al.
Publicado: (2013)

Real-time submillisecond single-molecule FRET dynamics of freely diffusing molecules with liposome tethering
por: Kim, Jae-Yeol, et al.
Publicado: (2015)

Enhancement of Energy Transfer Efficiency with Structural Control of Multichromophore Light‐Harvesting Assembly
por: Oh, Inhwan, et al.
Publicado: (2020)

The Photoactive Photosynthetic Reaction Center of a Rhodobacter sphaeroides Mutant Lacking 3-Vinyl (Bacterio)Chlorophyllide a Hydratase Contains 3-Vinyl Bacteriochlorophyll a
por: Kim, June, et al.
Publicado: (2023)

Protein energy landscapes determined by five-dimensional crystallography
por: Schmidt, Marius, et al.
Publicado: (2013)

Reaction dynamics studied via femtosecond X-ray liquidography at X-ray free-electron lasers
por: Choi, Eun Hyuk, et al.
Publicado: (2022)

protaTETHER – a method for the incorporation of variable linkers in protein fusions reveals impacts of linker flexibility in a PKAc‐GFP fusion protein
por: Norris, Jessica L., et al.
Publicado: (2018)

Synthesis of N-aryl amines enabled by photocatalytic dehydrogenation
por: Kim, Jungwon, et al.
Publicado: (2020)

Optimizing the enzymatic release of MMAE from isoDGR-based small molecule drug conjugate by incorporation of a GPLG-PABC enzymatically cleavable linker
por: Zambra, Marco, et al.
Publicado: (2023)

Photocleavable linker for the patterning of bioactive molecules
por: Wegner, Seraphine V., et al.
Publicado: (2015)

Solvent-modulated proton-coupled electron transfer in an iridium complex with an ESIPT ligand
por: Kim, Siin, et al.
Publicado: (2022)

Protein folding from heterogeneous unfolded state revealed by time-resolved X-ray solution scattering
por: Kim, Tae Wu, et al.
Publicado: (2020)

Structural Dynamics of C(2)F(4)I(2) in Cyclohexane Studied via Time-Resolved X-ray Liquidography
por: Gu, Jain, et al.
Publicado: (2021)

Linker-free incorporation of carbohydrates into in vitro displayed macrocyclic peptides
por: Jongkees, S. A. K., et al.
Publicado: (2017)

A New Methodology for Incorporating Chiral Linkers into Stapled Peptides
por: Serrano, Juan C., et al.
Publicado: (2017)

Determining the charge distribution and the direction of bond cleavage with femtosecond anisotropic x-ray liquidography
por: Heo, Jun, et al.
Publicado: (2022)

Filming ultrafast roaming-mediated isomerization of bismuth triiodide in solution
por: Choi, Eun Hyuk, et al.
Publicado: (2021)

Small Multitarget Molecules Incorporating the Enone Moiety
por: Liargkova, Thalia, et al.
Publicado: (2019)

Femtosecond X-ray solution scattering reveals that bond formation mechanism of a gold trimer complex is independent of excitation wavelength
por: Kim, Kyung Hwan, et al.
Publicado: (2016)

Cerium Photocatalyst in Action: Structural Dynamics in the Presence of Substrate Visualized via Time-Resolved X-ray Liquidography
por: Lee, Yunbeom, et al.
Publicado: (2023)

A High-Throughput Small Molecule Screen for C. elegans Linker Cell Death Inhibitors
por: Schwendeman, Andrew R., et al.
Publicado: (2016)

Design and characterization of structured protein linkers with differing flexibilities
por: Klein, Joshua S., et al.
Publicado: (2014)

Small molecule regulated dynamic structural changes of human G-quadruplexes
por: Debnath, Manish, et al.
Publicado: (2016)

Small molecules in regulating protein phase separation: Regulating protein phase separation by small molecules
por: Li, Siyang, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_8r61ursm9dgesifgaori3bfgkj