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Chenodeoxycholic Acid from Bile Inhibits Influenza A Virus Replication via Blocking Nuclear Export of Viral Ribonucleoprotein Complexes

Influenza A virus (IAV) infection is still a major global threat for humans, especially for the risk groups: young children and the elderly. The currently licensed antiviral drugs target viral factors and are prone to viral resistance. In recent years, a few endogenous small molecules from host, suc...

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Detalles Bibliográficos
Autores principales: Luo, Ling, Han, Weili, Du, Jinyan, Yang, Xia, Duan, Mubing, Xu, Chenggang, Zeng, Zhenling, Chen, Weisan, Chen, Jianxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6321071/
https://www.ncbi.nlm.nih.gov/pubmed/30558117
http://dx.doi.org/10.3390/molecules23123315