Sulfonamide Inhibition Studies of a New β-Carbonic Anhydrase from the Pathogenic Protozoan Entamoeba histolytica

A newly described β-carbonic anhydrase (CA, EC 4.2.1.1) from the pathogenic protozoan Entamoeba histolytica, EhiCA, was recently shown to possess a significant catalytic activity for the physiologic CO(2) hydration reaction (k(cat) of 6.7 × 10(5) s(−1) and a k(cat)/K(m) of 8.9 × 10(7) M(−1) s(−1))....

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Detalles Bibliográficos
Autores principales: Bua, Silvia, Haapanen, Susanna, Kuuslahti, Marianne, Parkkila, Seppo, Supuran, Claudiu T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6321117/
https://www.ncbi.nlm.nih.gov/pubmed/30544802
http://dx.doi.org/10.3390/ijms19123946

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6321117/
https://www.ncbi.nlm.nih.gov/pubmed/30544802
http://dx.doi.org/10.3390/ijms19123946

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