Cargando…

Hydrophilic Linear Peptide with Histidine and Lysine Residues as a Key Factor Affecting Antifungal Activity

Increases in the numbers of immunocompromised patients and the emergence of drug-resistance fungal pathogens have led to the need for new, safe, efficacious antifungal agents. In this study, we designed a histidine-lysine-lysine (HKK) motif and synthesized six HKK peptides with repetitions of the mo...

Descripción completa

Detalles Bibliográficos
Autores principales:	Park, Seong-Cheol, Kim, Jin-Young, Kim, Eun-Ji, Cheong, Gang-Won, Lee, Yongjae, Choi, Wonkyun, Lee, Jung Ro, Jang, Mi-Kyeong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6321124/ https://www.ncbi.nlm.nih.gov/pubmed/30486512 http://dx.doi.org/10.3390/ijms19123781

Ejemplares similares

Functional Mechanisms Underlying the Antimicrobial Activity of the Oryza sativa Trx-like Protein
por: Park, Seong-Cheol, et al.
Publicado: (2019)

Functional Characterization of a Rice Thioredoxin Protein OsTrxm and Its Cysteine Mutant Variant with Antifungal Activity
por: Park, Seong-Cheol, et al.
Publicado: (2019)

Improved Cell Selectivity of Pseudin-2 via Substitution in the Leucine-Zipper Motif: In Vitro and In Vivo Antifungal Activity
por: Park, Seong-Cheol, et al.
Publicado: (2020)

Antifungal Effect of A Chimeric Peptide Hn-Mc against Pathogenic Fungal Strains
por: Kim, Jin-Young, et al.
Publicado: (2020)

Lysine Scanning of Arg(10)–Teixobactin: Deciphering the Role of Hydrophobic and Hydrophilic Residues
por: Abdel Monaim, Shimaa A. H., et al.
Publicado: (2016)

Antifungal Mechanism of Vip3Aa, a Vegetative Insecticidal Protein, against Pathogenic Fungal Strains
por: Park, Seong-Cheol, et al.
Publicado: (2021)

Antifungal Action of Arabidopsis thaliana TCP21 via Induction of Oxidative Stress and Apoptosis
por: Park, Seong-Cheol, et al.
Publicado: (2023)

Pore‐Bound Water at the Key Residue Histidine 37 in Influenza A M2
por: Movellan, Kumar Tekwani, et al.
Publicado: (2021)

Stable Deuterium Labeling of Histidine-Rich Lysine-Based Dendrimers
por: Sheveleva, Nadezhda N., et al.
Publicado: (2019)

Antifungal and Anti-Inflammatory Activities of PS1-2 Peptide against Fluconazole-Resistant Candida albicans
por: Lee, Jong-Kook, et al.
Publicado: (2022)

Histidine Hydrogen-Deuterium Exchange Mass Spectrometry for Probing the Microenvironment of Histidine Residues in Dihydrofolate Reductase
por: Miyagi, Masaru, et al.
Publicado: (2011)

Histidine Residue 94 Is Involved in pH Sensing by Histidine Kinase ArsS of Helicobacter pylori
por: Müller, Stefanie, et al.
Publicado: (2009)

Micelles Based on Lysine, Histidine, or Arginine: Designing Structures for Enhanced Drug Delivery
por: Xie, Li, et al.
Publicado: (2021)

Anti-Biofilm Effects of Rationally Designed Peptides against Planktonic Cells and Pre-Formed Biofilm of Pseudomonas aeruginosa
por: Kim, Young-Min, et al.
Publicado: (2023)

Histidine Residues at the Active Site of the Pasteurella multocida Toxin
por: Pullinger, Gillian D, et al.
Publicado: (2007)

Anti-Biofilm Effects of Synthetic Antimicrobial Peptides Against Drug-Resistant Pseudomonas aeruginosa and Staphylococcus aureus Planktonic Cells and Biofilm
por: Park, Seong-Cheol, et al.
Publicado: (2019)

Identification of Lysine Histidine Transporter 2 as an 1-Aminocyclopropane Carboxylic Acid Transporter in Arabidopsis thaliana by Transgenic Complementation Approach
por: Choi, Jungki, et al.
Publicado: (2019)

Genetic Diversity and Population Structure of Nutria (Myocastor coypus) in South Korea
por: Kim, Il Ryong, et al.
Publicado: (2019)

Histidine-Rich Defensins from the Solanaceae and Brasicaceae Are Antifungal and Metal Binding Proteins
por: Bleackley, Mark R., et al.
Publicado: (2020)

NMR Studies of Two Lysine Based Dendrimers with Insertion of Similar Histidine-Arginine and Arginine-Histidine Spacers Having Different Properties for Application in Drug Delivery
por: Sheveleva, Nadezhda N., et al.
Publicado: (2023)

Mechanism of the pH-Induced Conformational Change in the Sensor Domain of the DraK Histidine Kinase via the E83, E105, and E107 Residues
por: Yeo, Kwon Joo, et al.
Publicado: (2014)

Potent Antifungal Functions of a Living Modified Organism Protein, CP4-EPSPS, against Pathogenic Fungal Cells
por: Park, Seong-Cheol, et al.
Publicado: (2023)

Genome-Wide Identification and Functional Analysis of Lysine Histidine Transporter (LHT) Gene Families in Maize
por: Rabby, Md. Golam, et al.
Publicado: (2022)

Residue–Residue Contact Can Be a Potential Feature for the Prediction of Lysine Crotonylation Sites
por: Wang, Rulan, et al.
Publicado: (2022)

Genetic variations in histidine-rich protein 2 and histidine-rich protein 3 of Myanmar Plasmodium falciparum isolates
por: Lê, Hương Giang, et al.
Publicado: (2020)

Role of Polymeric Endosomolytic Agents in Gene Transfection: A Comparative Study of Poly(l-lysine) Grafted with Monomeric l-Histidine Analogue and Poly(l-histidine)
por: Hwang, Hee Sook, et al.
Publicado: (2014)

Histidine residues at the copper-binding site in human tyrosinase are essential for its catalytic activities
por: Noh, Hyangsoon, et al.
Publicado: (2020)

Lysine Residue 185 of Rad1 Is a Topological but Not a Functional Counterpart of Lysine Residue 164 of PCNA
por: Wit, Niek, et al.
Publicado: (2011)

Hydrophilic Aromatic Residue and in silico Structure for Carbohydrate Binding Module
por: Chou, Wei-Yao, et al.
Publicado: (2011)

Candidacidal and Antibiofilm Activity of PS1-3 Peptide against Drug-Resistant Candida albicans on Contact Lenses
por: Lee, Jong-Kook, et al.
Publicado: (2022)

Gold(I) Weak Binding Sites: Histidine Residues of Serum Albumin
por: Xiao, J., et al.
Publicado: (1994)

Identification of Gut Microbial Lysine and Histidine Degradation and CYP-Dependent Metabolites as Biomarkers of Fatty Liver Disease
por: Driuchina, Anastasiia, et al.
Publicado: (2023)

Functional Characterization of an Arabidopsis Profilin Protein as a Molecular Chaperone under Heat Shock Stress
por: Son, Hyosuk, et al.
Publicado: (2022)

Design of Antimicrobial Peptides with Cell-Selective Activity and Membrane-Acting Mechanism against Drug-Resistant Bacteria
por: Park, Seong-Cheol, et al.
Publicado: (2022)

N(ε)-Carboxymethyl Modification of Lysine Residues in Pathogenic Prion Isoforms
por: Choi, Yeong-Gon, et al.
Publicado: (2015)

Enhancing Hydrophilicity of Thick Electrodes for High Energy Density Aqueous Batteries
por: Lee, Jungeun, et al.
Publicado: (2023)

Arginine and Lysine interactions with π residues in metalloproteins
por: Anitha, Parimelzaghan, et al.
Publicado: (2012)

Lysine-based dendrimer with double arginine residues
por: Sheveleva, Nadezhda N., et al.
Publicado: (2019)

Context‐Dependence of the Reactivity of Cysteine and Lysine Residues
por: Boll, Linus B., et al.
Publicado: (2022)

Histone Lysine Methylation and Neurodevelopmental Disorders
por: Kim, Jeong-Hoon, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_u928sjs03n2cf7vdkf5il57n5g