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Application of Real-Time Cell Electronic Analysis System in Modern Pharmaceutical Evaluation and Analysis
Objective: We summarized the progress of the xCELLigence real-time cell analysis (RTCA) technology application in recent years for the sake of enriching and developing the application of RTCA in the field of Chinese medicine. Background: The RTCA system is an established electronic cellular biosenso...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6321149/ https://www.ncbi.nlm.nih.gov/pubmed/30544947 http://dx.doi.org/10.3390/molecules23123280 |
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author | Yan, Guojun Du, Qian Wei, Xuchao Miozzi, Jackelyn Kang, Chen Wang, Jinnv Han, Xinxin Pan, Jinhuo Xie, Hui Chen, Jun Zhang, Weihua |
author_facet | Yan, Guojun Du, Qian Wei, Xuchao Miozzi, Jackelyn Kang, Chen Wang, Jinnv Han, Xinxin Pan, Jinhuo Xie, Hui Chen, Jun Zhang, Weihua |
author_sort | Yan, Guojun |
collection | PubMed |
description | Objective: We summarized the progress of the xCELLigence real-time cell analysis (RTCA) technology application in recent years for the sake of enriching and developing the application of RTCA in the field of Chinese medicine. Background: The RTCA system is an established electronic cellular biosensor. This system uses micro-electronic biosensor technology that is confirmed for real-time, label-free, dynamic and non-offensive monitoring of cell viability, migration, growth, spreading, and proliferation. Methods: We summarized the relevant experiments and literature of RTCA technology from the principles, characteristics, applications, especially from the latest application progress. Results and conclusion: RTCA is attracting more and more attention. Now it plays an important role in drug screening, toxicology, Chinese herbal medicine and so on. It has wide application prospects in the area of modern pharmaceutical evaluation and analysis. |
format | Online Article Text |
id | pubmed-6321149 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-63211492019-01-14 Application of Real-Time Cell Electronic Analysis System in Modern Pharmaceutical Evaluation and Analysis Yan, Guojun Du, Qian Wei, Xuchao Miozzi, Jackelyn Kang, Chen Wang, Jinnv Han, Xinxin Pan, Jinhuo Xie, Hui Chen, Jun Zhang, Weihua Molecules Review Objective: We summarized the progress of the xCELLigence real-time cell analysis (RTCA) technology application in recent years for the sake of enriching and developing the application of RTCA in the field of Chinese medicine. Background: The RTCA system is an established electronic cellular biosensor. This system uses micro-electronic biosensor technology that is confirmed for real-time, label-free, dynamic and non-offensive monitoring of cell viability, migration, growth, spreading, and proliferation. Methods: We summarized the relevant experiments and literature of RTCA technology from the principles, characteristics, applications, especially from the latest application progress. Results and conclusion: RTCA is attracting more and more attention. Now it plays an important role in drug screening, toxicology, Chinese herbal medicine and so on. It has wide application prospects in the area of modern pharmaceutical evaluation and analysis. MDPI 2018-12-11 /pmc/articles/PMC6321149/ /pubmed/30544947 http://dx.doi.org/10.3390/molecules23123280 Text en © 2018 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Yan, Guojun Du, Qian Wei, Xuchao Miozzi, Jackelyn Kang, Chen Wang, Jinnv Han, Xinxin Pan, Jinhuo Xie, Hui Chen, Jun Zhang, Weihua Application of Real-Time Cell Electronic Analysis System in Modern Pharmaceutical Evaluation and Analysis |
title | Application of Real-Time Cell Electronic Analysis System in Modern Pharmaceutical Evaluation and Analysis |
title_full | Application of Real-Time Cell Electronic Analysis System in Modern Pharmaceutical Evaluation and Analysis |
title_fullStr | Application of Real-Time Cell Electronic Analysis System in Modern Pharmaceutical Evaluation and Analysis |
title_full_unstemmed | Application of Real-Time Cell Electronic Analysis System in Modern Pharmaceutical Evaluation and Analysis |
title_short | Application of Real-Time Cell Electronic Analysis System in Modern Pharmaceutical Evaluation and Analysis |
title_sort | application of real-time cell electronic analysis system in modern pharmaceutical evaluation and analysis |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6321149/ https://www.ncbi.nlm.nih.gov/pubmed/30544947 http://dx.doi.org/10.3390/molecules23123280 |
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