Cargando…

Discovery of Non-Peptidic Compounds against Chagas Disease Applying Pharmacophore Guided Molecular Modelling Approaches

Chagas disease is one of the primary causes of heart diseases accounting to 50,000 lives annually and is listed as the neglected tropical disease. Because the currently available therapies have greater toxic effects with higher resistance, there is a dire need to develop new drugs to combat the dise...

Descripción completa

Detalles Bibliográficos
Autores principales: Rampogu, Shailima, Lee, Gihwan, Baek, Ayoung, Son, Minky, Park, Chanin, Zeb, Amir, Yoon, Sang Hwa, Park, Suhyeon, Lee, Keun Woo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6321154/
https://www.ncbi.nlm.nih.gov/pubmed/30469538
http://dx.doi.org/10.3390/molecules23123054