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Current Landscape and the Potential Role of Hypoxia-Inducible Factors and Selenium in Clear Cell Renal Cell Carcinoma Treatment

In the last two decades, the discovery of various pathways involved in renal cell carcinoma (RCC) has led to the development of biologically-driven targeted therapies. Hypoxia-inducible factors (HIFs), angiogenic growth factors, von Hippel–Lindau (VHL) gene mutations, and oncogenic microRNAs (miRNAs...

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Detalles Bibliográficos
Autores principales: Garje, Rohan, An, Josiah J., Sanchez, Kevin, Greco, Austin, Stolwijk, Jeffrey, Devor, Eric, Rustum, Youcef, Zakharia, Yousef
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6321165/
https://www.ncbi.nlm.nih.gov/pubmed/30513765
http://dx.doi.org/10.3390/ijms19123834