Cargando…

Jowiseungchungtang Inhibits Amyloid-β Aggregation and Amyloid-β-Mediated Pathology in 5XFAD Mice

Alzheimer’s disease (AD) is a neurodegenerative disease, which is accompanied by memory loss and cognitive dysfunction. Although a number of trials to treat AD are in progress, there are no drugs available that inhibit the progression of AD. As the aggregation of amyloid-β (Aβ) peptides in the brain...

Descripción completa

Detalles Bibliográficos
Autores principales:	Shin, Soo Jung, Jeong, Yu-on, Jeon, Seong Gak, Kim, Sujin, Lee, Seong-kyung, Nam, Yunkwon, Park, Yong Ho, Kim, Dabi, Lee, Youn Seok, Choi, Hong Seok, Kim, Jin-il, Kim, Jwa-Jin, Moon, Minho
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6321192/ https://www.ncbi.nlm.nih.gov/pubmed/30551564 http://dx.doi.org/10.3390/ijms19124026

Ejemplares similares

MK-0677, a Ghrelin Agonist, Alleviates Amyloid Beta-Related Pathology in 5XFAD Mice, an Animal Model of Alzheimer’s Disease
por: Jeong, Yu-on, et al.
Publicado: (2018)

Omega-3 Fatty Acid-Type Docosahexaenoic Acid Protects against Aβ-Mediated Mitochondrial Deficits and Pathomechanisms in Alzheimer’s Disease-Related Animal Model
por: Park, Yong Ho, et al.
Publicado: (2020)

Red Ginseng Attenuates Aβ-Induced Mitochondrial Dysfunction and Aβ-mediated Pathology in an Animal Model of Alzheimer’s Disease
por: Shin, Soo Jung, et al.
Publicado: (2019)

Platycodon grandiflorum Root Protects against Aβ-Induced Cognitive Dysfunction and Pathology in Female Models of Alzheimer’s Disease
por: Nam, Yunkwon, et al.
Publicado: (2021)

Mesoscopic Mapping of Visual Pathway in a Female 5XFAD Mouse Model of Alzheimer’s Disease
por: Nam, Yunkwon, et al.
Publicado: (2022)

Red Ginseng Inhibits Tau Aggregation and Promotes Tau Dissociation In Vitro
por: Shin, Soo Jung, et al.
Publicado: (2020)

Topographical Visualization of the Reciprocal Projection between the Medial Septum and the Hippocampus in the 5XFAD Mouse Model of Alzheimer’s Disease
por: Kim, Sujin, et al.
Publicado: (2019)

Tailoring Hydrophobic Interactions between Probes and Amyloid-β Peptides for Fluorescent Monitoring of Amyloid-β Aggregation
por: Kim, Sonam, et al.
Publicado: (2018)

Bilingualism for Dementia: Neurological Mechanisms Associated With Functional and Structural Changes in the Brain
por: Kim, Sujin, et al.
Publicado: (2019)

Early Detection of Aβ Deposition in the 5xFAD Mouse by Amyloid PET
por: Oh, Se Jong, et al.
Publicado: (2018)

Carprofen alleviates Alzheimer-like phenotypes of 5XFAD transgenic mice by targeting the pathological hallmarks induced by amyloid-β aggregation
por: Lee, Donghee, et al.
Publicado: (2023)

The Potential Roles of Ghrelin in Metabolic Syndrome and Secondary Symptoms of Alzheimer’s Disease
por: Kim, Sujin, et al.
Publicado: (2020)

How Do the Size, Charge and Shape of Nanoparticles Affect Amyloid β Aggregation on Brain Lipid Bilayer?
por: Kim, Yuna, et al.
Publicado: (2016)

Traditional Oriental Medicines and Alzheimer’s Disease
por: Jeon, Seong Gak, et al.
Publicado: (2019)

Alteration of Neural Pathways and Its Implications in Alzheimer’s Disease
por: Kim, Sujin, et al.
Publicado: (2022)

Erratum: How Do the Size, Charge and Shape of Nanoparticles Affect Amyloid β Aggregation on Brain Lipid Bilayer?
por: Kim, Yuna, et al.
Publicado: (2016)

Effective screen for amyloid β aggregation inhibitor using amyloid β-conjugated gold nanoparticles
por: Han, Sun-Ho, et al.
Publicado: (2011)

Fluorescent indolizine derivative YI-13 detects amyloid-β monomers, dimers, and plaques in the brain of 5XFAD Alzheimer transgenic mouse model
por: Kim, DaWon, et al.
Publicado: (2020)

Intrahippocampal injection of a lentiviral vector expressing neurogranin enhances cognitive function in 5XFAD mice
por: Jeon, Seong Gak, et al.
Publicado: (2018)

Thioflavin-positive tau aggregates complicating quantification of amyloid plaques in the brain of 5XFAD transgenic mouse model
por: Shin, Jisu, et al.
Publicado: (2021)

Phytoestrogen Coumestrol Selectively Inhibits Monoamine Oxidase-A and Amyloid β Self-Aggregation
por: Seong, Su Hui, et al.
Publicado: (2022)

Plasma Amyloid-β Oligomerization Tendency Predicts Amyloid PET Positivity
por: Pyun, Jung-Min, et al.
Publicado: (2021)

Characterization of age- and stage-dependent impaired adult subventricular neurogenesis in 5XFAD mouse model of Alzheimer’s disease
por: Park, Hyun Ha, et al.
Publicado: (2023)

Amyloid β-Sheet Mimics that Antagonize Amyloid Aggregation and Reduce Amyloid Toxicity
por: Cheng, Pin-Nan, et al.
Publicado: (2012)

Correction: Fluorescent indolizine derivative YI-13 detects amyloid-β monomers, dimers, and plaques in the brain of 5XFAD Alzheimer transgenic mouse model
por: Kim, DaWon, et al.
Publicado: (2021)

Brain Region-Specific Differences in Amyloid-β Plaque Composition in 5XFAD Mice
por: Bader, Angelika Sabine, et al.
Publicado: (2023)

Bleomycin modulates amyloid aggregation in β-amyloid and hIAPP
por: Kumari, Anchala, et al.
Publicado: (2020)

Shedding Light on Alzheimer’s β-Amyloidosis: Photosensitized Methylene Blue Inhibits Self-Assembly of β-Amyloid Peptides and Disintegrates Their Aggregates
por: Lee, Byung Il, et al.
Publicado: (2017)

Detection of β-amyloid aggregates/plaques in 5xFAD mice by labelled native PLGA nanoparticles: implication in the diagnosis of Alzheimer’s disease
por: Govindarajan, Karthivashan, et al.
Publicado: (2023)

Food protein-derived amyloids do not accelerate amyloid β aggregation
por: Rahman, M. Mahafuzur, et al.
Publicado: (2023)

Inhibition of Amyloid β-Induced Lipid Membrane Permeation and Amyloid β Aggregation by K162
por: Mrdenovic, Dusan, et al.
Publicado: (2021)

Structural Determinant of β-Amyloid Formation: From Transmembrane Protein Dimerization to β-Amyloid Aggregates
por: Papadopoulos, Nicolas, et al.
Publicado: (2022)

REDD1 Is Involved in Amyloid β-Induced Synaptic Dysfunction and Memory Impairment
por: Yi, Jee Hyun, et al.
Publicado: (2020)

Cerebrospinal Fluid Levels of β-Amyloid 40 and β-Amyloid 42 are Proportionately Decreased in Amyloid Positron-Emission Tomography Negative Idiopathic Normal-Pressure Hydrocephalus Patients
por: Kim, Hyun Jae, et al.
Publicado: (2019)

Relationship between adult subventricular neurogenesis and Alzheimer’s disease: Pathologic roles and therapeutic implications
por: Kim, Hyeon Soo, et al.
Publicado: (2022)

Impact of sphingosine and acetylsphingosines on the aggregation and toxicity of metal-free and metal-treated amyloid-β
por: Yi, Yelim, et al.
Publicado: (2020)

Nurr1 (NR4A2) regulates Alzheimer’s disease‐related pathogenesis and cognitive function in the 5XFAD mouse model
por: Moon, Minho, et al.
Publicado: (2018)

Inhibition of REV‐ERBs stimulates microglial amyloid‐beta clearance and reduces amyloid plaque deposition in the 5XFAD mouse model of Alzheimer’s disease
por: Lee, Jiyeon, et al.
Publicado: (2019)

Dynamic changes of oligomeric amyloid β levels in plasma induced by spiked synthetic Aβ(42)
por: An, Seong Soo A., et al.
Publicado: (2017)

Tau aggregation and its interplay with amyloid-β
por: Nisbet, Rebecca M., et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_idgbfjpguejjslkr0jesrimjgi