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Formulation of Bioerodible Ketamine Microparticles as an Analgesic Adjuvant Treatment Produced by Supercritical Fluid Polymer Encapsulation

Pain is inadequately relieved by escalating doses of a strong opioid analgesic such as morphine in up to 25% of patients with cancer-related severe pain complicated by a neuropathic (nerve damage) component. Hence, there is an unmet medical need for research on novel painkiller strategies. In the pr...

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Detalles Bibliográficos
Autores principales: Han, Felicity Y., Whittaker, Andrew K., Howdle, Steven M., Naylor, Andrew, Shabir-Ahmed, Anjumn, Zhang, Cheng, Smith, Maree T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6321204/
https://www.ncbi.nlm.nih.gov/pubmed/30563294
http://dx.doi.org/10.3390/pharmaceutics10040264