Cargando…
Characterization of Endocannabinoid-Metabolizing Enzymes in Human Peripheral Blood Mononuclear Cells under Inflammatory Conditions
Endocannabinoid-metabolizing enzymes are downregulated in response to lipopolysaccharide (LPS)-induced inflammation in mice, which may serve as a negative feedback mechanism to increase endocannabinoid levels and reduce inflammation. Increased plasma levels of the pro-inflammatory cytokine interleuk...
Autores principales: | Szafran, Brittany N., Lee, Jung Hwa, Borazjani, Abdolsamad, Morrison, Peter, Zimmerman, Grace, Andrzejewski, Kelly L., Ross, Matthew K., Kaplan, Barbara L.F. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6321211/ https://www.ncbi.nlm.nih.gov/pubmed/30513753 http://dx.doi.org/10.3390/molecules23123167 |
Ejemplares similares
-
Inactivation of CES1 Blocks Prostaglandin D(2) Glyceryl
Ester Catabolism in Monocytes/Macrophages and Enhances
Its Anti-inflammatory Effects, Whereas the Pro-inflammatory Effects
of Prostaglandin E(2) Glyceryl Ester Are Attenuated
por: Scheaffer, Hannah L., et al.
Publicado: (2020) -
Endocannabinoid levels in peripheral blood mononuclear cells of multiple sclerosis patients treated with dimethyl fumarate
por: Sánchez-Sanz, Alicia, et al.
Publicado: (2022) -
Effects of Toxicologically Relevant Xenobiotics and the Lipid-Derived Electrophile 4-Hydroxynonenal on Macrophage Cholesterol Efflux: Silencing Carboxylesterase 1 Has Paradoxical Effects on Cholesterol Uptake and Efflux
por: Ross, Matthew K., et al.
Publicado: (2014) -
The endocannabinoid hydrolase FAAH is an allosteric enzyme
por: Dainese, Enrico, et al.
Publicado: (2020) -
Endocannabinoid engagement of CB(2) regulates RSV-induced immunity
por: Kaplan, Barbara L. F.
Publicado: (2018)