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Construction of a Glutathione-Responsive and Silica-Based Nanocomposite for Controlled Release of Chelator Dimercaptosuccinic Acid

Dimercaptosuccinic acid (DMSA) is an oral heavy metal chelator. Although DMSA is the most acceptable chelator in the urinary excretion of toxic elements from children and adults, its defects in plasma binding and the membrane permeability limit its interaction with intracellular elements and affect...

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Detalles Bibliográficos
Autores principales: Zhai, Hongqiang, Wang, Yuli, Wang, Menghua, Liu, Shuai, Yu, Feifei, Gao, Chunsheng, Li, Guiling, Wu, Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6321213/
https://www.ncbi.nlm.nih.gov/pubmed/30487433
http://dx.doi.org/10.3390/ijms19123790