Cysteines and Disulfide-Bridged Macrocyclic Mimics of Teixobactin Analogues and Their Antibacterial Activity Evaluation against Methicillin-Resistant Staphylococcus Aureus (MRSA)

Teixobactin is a highly potent cyclic depsipeptide which kills a broad range of multi-drug resistant, Gram-positive bacteria, such as Methicillin-resistant Staphylococcus aureus (MRSA) without detectable resistance. In this work, we describe the design and rapid synthesis of novel teixobactin analog...

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Detalles Bibliográficos
Autores principales: Malkawi, Ruba, Iyer, Abhishek, Parmar, Anish, Lloyd, Daniel G., Leng Goh, Eunice Tze, Taylor, Edward J., Sarmad, Sarir, Madder, Annemieke, Lakshminarayanan, Rajamani, Singh, Ishwar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6321233/
https://www.ncbi.nlm.nih.gov/pubmed/30314324
http://dx.doi.org/10.3390/pharmaceutics10040183

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