Chitosan-Based Polyelectrolyte Complexes for Doxorubicin and Zoledronic Acid Combined Therapy to Overcome Multidrug Resistance

This study aimed to develop nanovectors co-encapsulating doxorubicin (Doxo) and zoledronic acid (Zol) for a combined therapy against Doxo-resistant tumors. Chitosan (CHI)-based polyelectrolyte complexes (PECs) prepared by ionotropic gelation technique were proposed. The influence of some experimenta...

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Detalles Bibliográficos
Autores principales: Giarra, Simona, Zappavigna, Silvia, Campani, Virginia, Abate, Marianna, Cossu, Alessia Maria, Leonetti, Carlo, Porru, Manuela, Mayol, Laura, Caraglia, Michele, De Rosa, Giuseppe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6321278/
https://www.ncbi.nlm.nih.gov/pubmed/30304840
http://dx.doi.org/10.3390/pharmaceutics10040180

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6321278/
https://www.ncbi.nlm.nih.gov/pubmed/30304840
http://dx.doi.org/10.3390/pharmaceutics10040180

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