Hydrophobic Amino Acid Tryptophan Shows Promise as a Potential Absorption Enhancer for Oral Delivery of Biopharmaceuticals

Cell-penetrating peptides (CPPs) have great potential to efficiently deliver drug cargos across cell membranes without cytotoxicity. Cationic arginine and hydrophobic tryptophan have been reported to be key component amino acids for cellular internalization of CPPs. We recently found that l-arginine...

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Detalles Bibliográficos
Autores principales: Kamei, Noriyasu, Tamiwa, Hideyuki, Miyata, Mari, Haruna, Yuta, Matsumura, Koyo, Ogino, Hideyuki, Hirano, Serena, Higashiyama, Kazuhiro, Takeda-Morishita, Mariko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6321321/
https://www.ncbi.nlm.nih.gov/pubmed/30308982
http://dx.doi.org/10.3390/pharmaceutics10040182

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