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Simultaneous Quantitation of Isoprenoid Pyrophosphates in Plasma and Cancer Cells Using LC-MS/MS

Isoprenoids (IsoP) are an important class of molecules involved in many different cellular processes including cholesterol synthesis. We have developed a sensitive and specific LC-MS/MS method for the quantitation of three key IsoPs in bio-matrices, geranyl pyrophosphate (GPP), farnesyl pyrophosphat...

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Detalles Bibliográficos
Autores principales: Chhonker, Yashpal S., Haney, Staci L., Bala, Veenu, Holstein, Sarah A., Murry, Daryl J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6321327/
https://www.ncbi.nlm.nih.gov/pubmed/30544938
http://dx.doi.org/10.3390/molecules23123275