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Development of Spermatogenesis In Vitro in Three-Dimensional Culture from Spermatogonial Cells of Busulfan-Treated Immature Mice

Aggressive chemotherapy may lead to permanent male infertility. Prepubertal males do not generate sperm, but their testes do contain spermatogonial cells (SPGCs) that could be used for fertility preservation. In the present study, we examined the effect of busulfan (BU) on the SPGCs of immature mice...

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Detalles Bibliográficos
Autores principales: AbuMadighem, Ali, Solomon, Ronnie, Stepanovsky, Alina, Kapelushnik, Joseph, Shi, QingHua, Meese, Eckart, Lunenfeld, Eitan, Huleihel, Mahmoud
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6321353/
https://www.ncbi.nlm.nih.gov/pubmed/30501072
http://dx.doi.org/10.3390/ijms19123804