Cargando…

Kinetics of the Solution-Mediated Polymorphic Transformation of the Novel l-Carnitine Orotate Polymorph, Form-II

Research studies related to the polymorphs of l-Carnitine orotate (CO), a medication used for the treatment and prevention of liver diseases, are insignificant or almost nonexistent. Accordingly, in the present study, l-Carnitine orotate (CO) was prepared for investigating CO polymorphs. Here, a rea...

Descripción completa

Detalles Bibliográficos
Autores principales:	An, Ji-Hun, Youn, Wonno, Kiyonga, Alice Nguvoko, Lim, Changjin, Park, Minho, Suh, Young-Ger, Ryu, Hyung Chul, Kim, Jae Sun, Park, Chun-Woong, Jung, Kiwon
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6321437/ https://www.ncbi.nlm.nih.gov/pubmed/30275413 http://dx.doi.org/10.3390/pharmaceutics10040171

Ejemplares similares

Co-Amorphous Screening for the Solubility Enhancement of Poorly Water-Soluble Mirabegron and Investigation of Their Intermolecular Interactions and Dissolution Behaviors
por: An, Ji-Hun, et al.
Publicado: (2018)

Rapid and Efficient Separation of Decursin and Decursinol Angelate from Angelica gigas Nakai using Ionic Liquid, (BMIm)BF(4), Combined with Crystallization
por: Kiyonga, Alice Nguvoko, et al.
Publicado: (2019)

Crystal Structure Analysis of the First Discovered Stability-Enhanced Solid State of Tenofovir Disoproxil Free Base Using Single Crystal X-ray Diffraction
por: An, Ji-Hun, et al.
Publicado: (2017)

Facile and Rapid Isolation of Oxypeucedanin Hydrate and Byakangelicin from Angelica dahurica by Using [Bmim]Tf(2)N Ionic Liquid
por: Kiyonga, Alice Nguvoko, et al.
Publicado: (2021)

An Efficient Ionic Liquid-Mediated Extraction and Enrichment of Isoimperatorin from Ostericum koreanum (Max.) Kitagawa
por: Kiyonga, Alice Nguvoko, et al.
Publicado: (2021)

The Role of Carnitine Orotate Complex in Fatty Liver
por: Yi, Hyon-Seung
Publicado: (2021)

Carnitine Orotate Complex Ameliorates Insulin Resistance and Hepatic Steatosis Through Carnitine Acetyltransferase Pathway
por: Hong, Jung-Hee, et al.
Publicado: (2021)

Prolonged Use of Carnitine-Orotate Complex (Godex(®)) Is Associated with Improved Mortality: A Nationwide Cohort Study
por: Park, Kye-Yeung, et al.
Publicado: (2022)

Cytosinium orotate dihydrate
por: Portalone, Gustavo
Publicado: (2012)

Redetermination of orotic acid monohydrate
por: Portalone, Gustavo
Publicado: (2008)

A Facile Fluorometric Assay of Orotate Phosphoribosyltransferase Activity Using a Selective Fluorogenic Reaction for Orotic Acid
por: Shibata, Takayuki, et al.
Publicado: (2023)

Ultrasound-assisted theophylline polymorphic transformation: Selective polymorph nucleation, molecular mechanism and kinetics analysis
por: Fang, Chen, et al.
Publicado: (2021)

Inhibition of androgen receptor can decrease fat metabolism by decreasing carnitine palmitoyltransferase I levels in skeletal muscles of trained mice
por: Kim, Jisu, et al.
Publicado: (2019)

β-Alanine and orotate as supplements for cardiac protection
por: McCarty, Mark F, et al.
Publicado: (2014)

Hereditary orotic aciduria identified by newborn screening
por: Staretz-Chacham, Orna, et al.
Publicado: (2023)

Expression of thymidylate synthase and orotate phosphoribosyltransferase in thymic carcinoma
por: YOKOTA, KEISUKE, et al.
Publicado: (2012)

Lithium orotate: A superior option for lithium therapy?
por: Pacholko, Anthony G., et al.
Publicado: (2021)

The Synthesis of Orotic Acid-C(14)O(2)H
por: Langley, B. W.
Publicado: (1954)

Incorporation of Orotic Acid into Ribonucleotides and Ribonucleic Acid by Liver Tumours
por: Reid, E.
Publicado: (1958)

Identification and Semi-Synthesis of 3-O-Protocatechuoylceanothic Acid, a Novel and Natural GPR120 Agonist †
por: Lim, Changjin, et al.
Publicado: (2019)

Comment on “Influence of Orotate Phosphoribosyl Transferase Levels on Tumor Prognosis and Response to Chemotherapy”
por: Kapoor, Shailendra
Publicado: (2012)

Structure of Plasmodium falciparum orotate phosphoribosyltransferase with autologous inhibitory protein–protein interactions
por: Kumar, Shiva, et al.
Publicado: (2015)

Systemic primary carnitine deficiency with hypoglycemic encephalopathy
por: Jun, Jae Sung, et al.
Publicado: (2016)

TNFB Gene Polymorphism in Patients with Systemic Lupus Erythematosus in Korean
por: Kim, Ho-Youn, et al.
Publicado: (1995)

Tooth loss and adiposity: possible role of carnitine transporter (OCTN1/2) polymorphisms in women but not in men
por: Meisel, Peter, et al.
Publicado: (2020)

Efficacy and Safety of Tenofovir Disoproxil Orotate in Chronic Hepatitis B Patients Previously Treated with Tenofovir Disoproxil Fumarate: Multicenter, Open-Label, Prospective Study
por: Chang, Young, et al.
Publicado: (2021)

Kinetic Trapping of Metastable Amino Acid Polymorphs
por: Chowdhury, Azhad U., et al.
Publicado: (2014)

ISOLATION AND CHARACTERIZATION OF LOW DENSITY STRUCTURES FROM OROTIC ACID-INDUCED FATTY LIVERS
por: Rajalakshmi, Srinivasan, et al.
Publicado: (1969)

Structural Properties, Order–Disorder Phenomena, and Phase Stability of Orotic Acid Crystal Forms
por: Braun, Doris E., et al.
Publicado: (2016)

Photodegradation and Biodegradation of Poly(Lactic) Acid Containing Orotic Acid as a Nucleation Agent
por: Salač, Jan, et al.
Publicado: (2019)

Mild orotic aciduria in UMPS heterozygotes: a metabolic finding without clinical consequences
por: Wortmann, Saskia B., et al.
Publicado: (2017)

The Strange Case of Orotic Acid: The Different Expression of Pyrimidines Biosynthesis in Healthy Males and Females
por: Chiara, Francesco, et al.
Publicado: (2023)

Preferential Nucleation during Polymorphic Transformations
por: Sharma, H., et al.
Publicado: (2016)

Carnitine acetyltransferase deficiency mediates mitochondrial dysfunction‐induced cellular senescence in dermal fibroblasts
por: Song, Min Ji, et al.
Publicado: (2023)

Correction to: Tooth loss and adiposity: possible role of carnitine transporter (OCTN1/2) polymorphisms in women but not in men
por: Meisel, Peter, et al.
Publicado: (2021)

Dihydro-orotate dehydrogenase is physically associated with the respiratory complex and its loss leads to mitochondrial dysfunction
por: Fang, JingXian, et al.
Publicado: (2013)

Dietary sea cucumber cerebroside alleviates orotic acid-induced excess hepatic adipopexis in rats
por: Zhang, Bei, et al.
Publicado: (2012)

Protein instability and functional defects caused by mutations of dihydro-orotate dehydrogenase in Miller syndrome patients
por: Fang, JingXian, et al.
Publicado: (2012)

Reaction Mechanism and Substrate Specificity of Iso-orotate Decarboxylase: A Combined Theoretical and Experimental Study
por: Sheng, Xiang, et al.
Publicado: (2018)

Orotic acid-treated hepatocellular carcinoma cells resist steatosis by modification of fatty acid metabolism
por: Matilainen, Johanna, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_5152vjpm2lpd8se7rcvi1pc5te