Cargando…

Loss of Mitochondrial AAA Proteases AFG3L2 and YME1L Impairs Mitochondrial Structure and Respiratory Chain Biogenesis

Mitochondrial protein quality control is crucial for the maintenance of correct mitochondrial homeostasis. It is ensured by several specific mitochondrial proteases located across the various mitochondrial subcompartments. Here, we focused on characterization of functional overlap and cooperativity...

Descripción completa

Detalles Bibliográficos
Autores principales:	Cesnekova, Jana, Rodinova, Marie, Hansikova, Hana, Zeman, Jiri, Stiburek, Lukas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6321463/ https://www.ncbi.nlm.nih.gov/pubmed/30544562 http://dx.doi.org/10.3390/ijms19123930

Ejemplares similares

YME1L controls the accumulation of respiratory chain subunits and is required for apoptotic resistance, cristae morphogenesis, and cell proliferation
por: Stiburek, Lukas, et al.
Publicado: (2012)

LACE1 interacts with p53 and mediates its mitochondrial translocation and apoptosis
por: Cesnekova, Jana, et al.
Publicado: (2016)

Mouse brain expression patterns of Spg7, Afg3l1, and Afg3l2 transcripts, encoding for the mitochondrial m-AAA protease
por: Sacco, Tiziana, et al.
Publicado: (2010)

Loss of the mitochondrial i‐AAA protease YME1L leads to ocular dysfunction and spinal axonopathy
por: Sprenger, Hans‐Georg, et al.
Publicado: (2018)

The i-AAA protease YME1L and OMA1 cleave OPA1 to balance mitochondrial fusion and fission
por: Anand, Ruchika, et al.
Publicado: (2014)

Down‐regulation of the mitochondrial i‐AAA protease Yme1L induces muscle atrophy via FoxO3a and myostatin activation
por: Lee, Yoo Jeong, et al.
Publicado: (2019)

Loss of Yme1L perturbates mitochondrial dynamics
por: Ruan, Y, et al.
Publicado: (2013)

Whole-Exome Sequencing Identifies Homozygous AFG3L2 Mutations in a Spastic Ataxia-Neuropathy Syndrome Linked to Mitochondrial m-AAA Proteases
por: Pierson, Tyler Mark, et al.
Publicado: (2011)

Role of the AAA protease Yme1 in folding of proteins in the intermembrane space of mitochondria
por: Schreiner, Bernadette, et al.
Publicado: (2012)

Inactivation of the mitochondrial protease Afg3l2 results in severely diminished respiratory chain activity and widespread defects in mitochondrial gene expression
por: Pareek, Gautam, et al.
Publicado: (2020)

Mutations in the m-AAA proteases AFG3L2 and SPG7 are causing isolated dominant optic atrophy
por: Charif, Majida, et al.
Publicado: (2020)

Correction: Whole-Exome Sequencing Identifies Homozygous AFG3L2 Mutations in a Spastic Ataxia-Neuropathy Syndrome Linked to Mitochondrial m-AAA Proteases
por: Pierson, Tyler Mark, et al.
Publicado: (2013)

Multifunctional Mitochondrial AAA Proteases
por: Glynn, Steven E.
Publicado: (2017)

Mitochondrial Tim9 protects Tim10 from degradation by the protease Yme1
por: Spiller, Michael P., et al.
Publicado: (2015)

Deterioration of mitochondrial bioenergetics and ultrastructure impairment in skeletal muscle of a transgenic minipig model in the early stages of Huntington's disease
por: Rodinova, Marie, et al.
Publicado: (2019)

PW03-008 – Mitochondrial disturbances in Schnitzler syndrome
por: Sediva, A, et al.
Publicado: (2013)

Yme2, a putative RNA recognition motif and AAA+ domain containing protein, genetically interacts with the mitochondrial protein export machinery
por: Sharma, Nupur, et al.
Publicado: (2022)

AAA Proteases: Guardians of Mitochondrial Function and Homeostasis
por: Opalińska, Magdalena, et al.
Publicado: (2018)

Fluorescence Methods Applied to the Description of Urea-Dependent YME1L Protease Unfolding
por: Moore, Sydney, et al.
Publicado: (2020)

Homozygous YME1L1 mutation causes mitochondriopathy with optic atrophy and mitochondrial network fragmentation
por: Hartmann, Bianca, et al.
Publicado: (2016)

m-AAA proteases, mitochondrial calcium homeostasis and neurodegeneration
por: Patron, Maria, et al.
Publicado: (2018)

Mitochondrial inner-membrane protease Yme1 degrades outer-membrane proteins Tom22 and Om45
por: Wu, Xi, et al.
Publicado: (2018)

Tumor suppressor KIF1Bβ regulates mitochondrial apoptosis in collaboration with YME1L1
por: Ando, Koji, et al.
Publicado: (2019)

Knock-down of YME1L1 induces mitochondrial dysfunction during early porcine embryonic development
por: Zhou, Dongjie, et al.
Publicado: (2023)

ROMO1 is a constituent of the human presequence translocase required for YME1L protease import
por: Richter, Frank, et al.
Publicado: (2019)

OPA1 processing controls mitochondrial fusion and is regulated by mRNA splicing, membrane potential, and Yme1L
por: Song, Zhiyin, et al.
Publicado: (2007)

The Mitochondrial m-AAA Protease Prevents Demyelination and Hair Greying
por: Wang, Shuaiyu, et al.
Publicado: (2016)

AAA+ proteases: the first line of defense against mitochondrial damage
por: Pareek, Gautam
Publicado: (2022)

Caveolin-1 controls mitochondrial function through regulation of m-AAA mitochondrial protease
por: Volonte, Daniela, et al.
Publicado: (2016)

The relationship of mitochondrial dysfunction and the development of insulin resistance in Cushing’s syndrome
por: Ježková, Jana, et al.
Publicado: (2019)

Respiratory dysfunction by AFG3L2 deficiency causes decreased mitochondrial calcium uptake via organellar network fragmentation
por: Maltecca, Francesca, et al.
Publicado: (2012)

Sirt3 mitigates LPS‐induced mitochondrial damage in renal tubular epithelial cells by deacetylating YME1L1
por: Jian, Yonghong, et al.
Publicado: (2022)

Engineered AAA+ proteases reveal principles of proteolysis at the mitochondrial inner membrane
por: Shi, Hui, et al.
Publicado: (2016)

Increased nuclear DNA damage precedes mitochondrial dysfunction in peripheral blood mononuclear cells from Huntington’s disease patients
por: Askeland, Georgina, et al.
Publicado: (2018)

A novel AFG3L2 mutation close to AAA domain leads to aberrant OMA1 and OPA1 processing in a family with optic atrophy
por: Baderna, Valentina, et al.
Publicado: (2020)

Understanding the Role of Yeast Yme1 in Mitochondrial Function Using Biochemical and Proteomics Analyses
por: Kan, Kwan Ting, et al.
Publicado: (2022)

Multisystem mitochondrial diseases due to mutations in mtDNA-encoded subunits of complex I
por: Danhelovska, Tereza, et al.
Publicado: (2020)

Noninvasive diagnostics of mitochondrial disorders in isolated lymphocytes with high resolution respirometry
por: Pecina, Petr, et al.
Publicado: (2014)

Microarray and qPCR Analysis of Mitochondrial Metabolism Activation during Prenatal and Early Postnatal Development in Rats and Humans with Emphasis on CoQ(10) Biosynthesis
por: Krizova, Jana, et al.
Publicado: (2021)

Loss of the Drosophilam-AAA mitochondrial protease paraplegin results in mitochondrial dysfunction, shortened lifespan, and neuronal and muscular degeneration
por: Pareek, Gautam, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_lmd5gnvut5chas4oe5ag612puk