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Flurbiprofen-Loaded Solid SNEDDS Preconcentrate for the Enhanced Solubility, In-Vitro Dissolution and Bioavailability in Rats
The aim of this work was to prepare and optimize a solid self-nanoemulsifying drug delivery system pre-concentrate (SSP) containing water-insoluble flurbiprofen (FL) using a novel pseudo-ternary phase diagram. The pseudo-ternary phase diagram, composed of FL as the drug and dispersion core, Kollisol...
Autores principales: | Kim, Rae Man, Jang, Dong-Jin, Kim, Yu Chul, Yoon, Jin-Ha, Min, Kyoung Ah, Maeng, Han-Joo, Cho, Kwan Hyung |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6321466/ https://www.ncbi.nlm.nih.gov/pubmed/30487449 http://dx.doi.org/10.3390/pharmaceutics10040247 |
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