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Evaluation of β-Sitosterol Loaded PLGA and PEG-PLA Nanoparticles for Effective Treatment of Breast Cancer: Preparation, Physicochemical Characterization, and Antitumor Activity

β-Sitosterol (β-Sit) is a dietary phytosterol with demonstrated anticancer activity against a panel of cancers, but its poor solubility in water limits its bioavailability and therapeutic efficacy. In this study, poly(lactide-co-glycolic acid) (PLGA) and block copolymers of poly(ethylene glycol)-blo...

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Detalles Bibliográficos
Autores principales:	Andima, Moses, Costabile, Gabriella, Isert, Lorenz, Ndakala, Albert J., Derese, Solomon, Merkel, Olivia M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6321471/ https://www.ncbi.nlm.nih.gov/pubmed/30445705 http://dx.doi.org/10.3390/pharmaceutics10040232

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