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Optimized Chitosan/Anion Polyelectrolyte Complex Based Inserts for Vaginal Delivery of Fluconazole: In Vitro/In Vivo Evaluation

(1) Background: Fluconazole, used orally for vaginal candidiasis, has reported gastrointestinal side effects. Therefore, researchers directed towards the drug vaginal delivery. However, vaginal delivery is limited by poor retention and leakage. Thus, this work aimed at exploring chitosan/anion polye...

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Detalles Bibliográficos
Autores principales: Darwesh, Bayan, Aldawsari, Hibah M., Badr-Eldin, Shaimaa M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6321472/
https://www.ncbi.nlm.nih.gov/pubmed/30424501
http://dx.doi.org/10.3390/pharmaceutics10040227