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Heterogeneity in Colorectal Cancer: A Challenge for Personalized Medicine?

High inter-patient variability and high spatial heterogeneity are features of colorectal cancer (CRC). This may influence the molecular characterization of tumor tissue, now mandatory for patients with metastatic CRC who are candidates for treatment with an anti-EGFR mAb, as false-negative results c...

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Detalles Bibliográficos
Autores principales: Molinari, Chiara, Marisi, Giorgia, Passardi, Alessandro, Matteucci, Laura, De Maio, Giulia, Ulivi, Paola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6321493/
https://www.ncbi.nlm.nih.gov/pubmed/30477151
http://dx.doi.org/10.3390/ijms19123733

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