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Heterogeneity in Colorectal Cancer: A Challenge for Personalized Medicine?
High inter-patient variability and high spatial heterogeneity are features of colorectal cancer (CRC). This may influence the molecular characterization of tumor tissue, now mandatory for patients with metastatic CRC who are candidates for treatment with an anti-EGFR mAb, as false-negative results c...
Autores principales: | Molinari, Chiara, Marisi, Giorgia, Passardi, Alessandro, Matteucci, Laura, De Maio, Giulia, Ulivi, Paola |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6321493/ https://www.ncbi.nlm.nih.gov/pubmed/30477151 http://dx.doi.org/10.3390/ijms19123733 |
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