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An Intrinsic Mitochondrial Pathway Is Required for Phytic Acid-Chitosan-Iron Oxide Nanocomposite (Phy-CS-MNP) to Induce G(0)/G(1) Cell Cycle Arrest and Apoptosis in the Human Colorectal Cancer (HT-29) Cell Line
Magnetic iron oxide nanoparticles are among the most useful metal nanoparticles in biomedical applications. A previous study had confirmed that phytic acid-chitosan-iron oxide nanocomposite (Phy-CS-MNP) exhibited antiproliferative activity towards human colorectal cancer (HT-29) cells. Hence, in thi...
Autores principales: | Tan, Bee Ling, Norhaizan, Mohd Esa, Chan, Lee Chin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6321496/ https://www.ncbi.nlm.nih.gov/pubmed/30360519 http://dx.doi.org/10.3390/pharmaceutics10040198 |
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