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Modeling of Disintegration and Dissolution Behavior of Mefenamic Acid Formulation Using Numeric Solution of Noyes-Whitney Equation with Cellular Automata on Microtomographic and Algorithmically Generated Surfaces
Manufacturing parameters may have a strong impact on the dissolution and disintegration of solid dosage forms. In line with process analytical technology (PAT) and quality by design approaches, computer-based technologies can be used to design, control, and improve the quality of pharmaceutical comp...
Autores principales: | Yokoyama, Reiji, Kimura, Go, Schlepütz, Christian M., Huwyler, Jörg, Puchkov, Maxim |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6321502/ https://www.ncbi.nlm.nih.gov/pubmed/30513888 http://dx.doi.org/10.3390/pharmaceutics10040259 |
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