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l-Cysteine and l-Serine Modified Dendrimer with Multiple Reduced Thiols as a Kidney-Targeting Reactive Oxygen Species Scavenger to Prevent Renal Ischemia/Reperfusion Injury

l-cysteine (Cys)- and l-serine (Ser)-modified, third-generation polyamidoamine (PAMAM) dendrimer with multiple reduced thiols (Ser-PAMAM-Cys) was synthesized as a kidney-targeting reactive oxygen species (ROS) scavenger to help prevent renal ischemia/reperfusion injury. Ser-PAMAM-Cys effectively sca...

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Detalles Bibliográficos
Autores principales:	Matsuura, Satoru, Katsumi, Hidemasa, Suzuki, Hiroe, Hirai, Natsuko, Takashima, Rie, Morishita, Masaki, Sakane, Toshiyasu, Yamamoto, Akira
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6321508/ https://www.ncbi.nlm.nih.gov/pubmed/30513734 http://dx.doi.org/10.3390/pharmaceutics10040251

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