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Cloning, Characterization and Anion Inhibition Studies of a β-Carbonic Anhydrase from the Pathogenic Protozoan Entamoeba histolytica

We report the cloning and catalytic activity of a β-carbonic anhydrase (CA, EC 4.2.1.1), isolated from the pathogenic protozoan Entamoeba histolytica, EhiCA. This enzyme has a high catalytic activity for the physiologic CO(2) hydration reaction, with a k(cat) of 6.7 × 10(5) s(−1) and a k(cat)/K(m) o...

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Detalles Bibliográficos
Autores principales:	Haapanen, Susanna, Bua, Silvia, Kuuslahti, Marianne, Parkkila, Seppo, Supuran, Claudiu T.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6321543/ https://www.ncbi.nlm.nih.gov/pubmed/30486513 http://dx.doi.org/10.3390/molecules23123112

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