Cargando…

Deuterated Arachidonic Acids Library for Regulation of Inflammation and Controlled Synthesis of Eicosanoids: An In Vitro Study

The synthesis of signal lipids, including eicosanoids, is not fully understood, although it is key to the modulation of various inflammatory states. Recently, isotopologues of essential polyunsaturated fatty acids (PUFAs) deuterated at bis-allylic positions (D-PUFAs) have been proposed as inhibitors...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chistyakov, Dmitry V., Filimonov, Ivan S., Azbukina, Nadezhda V., Goriainov, Sergei V., Chistyakov, Viktor V., Fomich, Maksim A., Bekish, Andrei V., Shmanai, Vadim V., Sergeeva, Marina G., Shchepinov, Mikhail S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6321560/ https://www.ncbi.nlm.nih.gov/pubmed/30558277 http://dx.doi.org/10.3390/molecules23123331

Ejemplares similares

Sex-Mediated Differences in LPS Induced Alterations of TNFα, IL-10 Expression, and Prostaglandin Synthesis in Primary Astrocytes
por: Chistyakov, Dmitry V., et al.
Publicado: (2018)

High and Low Molecular Weight Hyaluronic Acid Differentially Influences Oxylipins Synthesis in Course of Neuroinflammation
por: Chistyakov, Dmitry V., et al.
Publicado: (2019)

Cellular Model of Endotoxin Tolerance in Astrocytes: Role of Interleukin 10 and Oxylipins
por: Chistyakov, Dmitry V., et al.
Publicado: (2019)

Deuterated Arachidonic Acid Ameliorates Lipopolysaccharide-Induced Lung Damage in Mice
por: Molchanova, Alla Y., et al.
Publicado: (2022)

Oxylipin Profiles as Functional Characteristics of Acute Inflammatory Responses in Astrocytes Pre-Treated with IL-4, IL-10, or LPS
por: Chistyakov, Dmitry V., et al.
Publicado: (2020)

Oxylipin Profiles in Plasma of Patients with Wilson’s Disease
por: Azbukina, Nadezhda V., et al.
Publicado: (2020)

Targeted Lipidomic Analysis of Aqueous Humor Reveals Signaling Lipid-Mediated Pathways in Primary Open-Angle Glaucoma
por: Azbukina, Nadezhda V., et al.
Publicado: (2021)

Comparison of PPAR Ligands as Modulators of Resolution of Inflammation, via Their Influence on Cytokines and Oxylipins Release in Astrocytes
por: Chistyakov, Dmitry V., et al.
Publicado: (2020)

High Glucose Shifts the Oxylipin Profiles in the Astrocytes towards Pro-Inflammatory States
por: Chistyakov, Dmitry V., et al.
Publicado: (2021)

Mechanisms and Treatment of Light-Induced Retinal Degeneration-Associated Inflammation: Insights from Biochemical Profiling of the Aqueous Humor
por: Chistyakov, Dmitry V., et al.
Publicado: (2020)

Inhibitor of Hyaluronic Acid Synthesis 4-Methylumbelliferone as an Anti-Inflammatory Modulator of LPS-Mediated Astrocyte Responses
por: Chistyakov, Dmitry V., et al.
Publicado: (2020)

Inflammation in Dry Eye Syndrome: Identification and Targeting of Oxylipin-Mediated Mechanisms
por: Chistyakov, Dmitry V., et al.
Publicado: (2020)

Rosiglitazone as a Modulator of TLR4 and TLR3 Signaling Pathways in Rat Primary Neurons and Astrocytes
por: Chistyakov, Dmitry V., et al.
Publicado: (2018)

Modulation of the Primary Astrocyte-Enriched Cultures’ Oxylipin Profiles Reduces Neurotoxicity
por: Guryleva, Mariia V., et al.
Publicado: (2021)

ARGEOS: A New Bioinformatic Tool for Detailed Systematics Search in GEO and ArrayExpress
por: Gavrish, Gleb E., et al.
Publicado: (2021)

Deuterated Polyunsaturated Fatty Acids Reduce Oxidative Stress and Extend the Lifespan of C. elegans
por: Beaudoin-Chabot, Caroline, et al.
Publicado: (2019)

Investigation of the Role of PUFA Metabolism in Breast Cancer Using a Rank-Based Random Forest Algorithm
por: Guryleva, Mariia V., et al.
Publicado: (2022)

Multi-Omics Approach Points to the Importance of Oxylipins Metabolism in Early-Stage Breast Cancer
por: Chistyakov, Dmitry V., et al.
Publicado: (2022)

FINO(2) Initiates Ferroptosis Through GPX4 Inactivation and Iron Oxidation
por: Gaschler, Michael M., et al.
Publicado: (2018)

Application of Underdetermined Differential Algebraic Equations to Solving One Problem from Heat Mass Transfer
por: Chistyakov, Viktor F., et al.
Publicado: (2020)

Binders Used for the Manufacturing of Composite Materials by Liquid Composite Molding
por: Terekhov, Ivan V., et al.
Publicado: (2021)

Radiative cooling of H(3)O(+) and its deuterated isotopologues
por: Melnikov, Vladlen V., et al.
Publicado: (2016)

Eicosanoids Derived From Arachidonic Acid and Their Family Prostaglandins and Cyclooxygenase in Psychiatric Disorders
por: Yui, Kunio, et al.
Publicado: (2015)

Bis-allylic Deuterated DHA Alleviates Oxidative Stress in Retinal Epithelial Cells
por: Rosell, Mélissa, et al.
Publicado: (2019)

Inhibitors of Oxidative Phosphorylation Modulate Astrocyte Inflammatory Responses through AMPK-Dependent Ptgs2 mRNA Stabilization
por: Astakhova, Alina, et al.
Publicado: (2019)

Plasma and urinary concentrations of arachidonic acid-derived eicosanoids are associated with diabetic kidney disease
por: Mota-Zamorano, Sonia, et al.
Publicado: (2021)

Possible Mechanisms of Fullerene C(60) Antioxidant Action
por: Chistyakov, V. A., et al.
Publicado: (2013)

Impact of Deuteration and Temperature on Furan Ring Dynamics
por: Dopieralski, Przemyslaw, et al.
Publicado: (2021)

Polymorphisms in the Mn-SOD and EC-SOD Genes and Their Relationship to Diabetic Neuropathy in Type 1 Diabetes Mellitus
por: Chistyakov, Dimitry A, et al.
Publicado: (2001)

Metabolic Fingerprinting Links Oncogenic PIK3CA with Enhanced Arachidonic Acid-Derived Eicosanoids
por: Koundouros, Nikos, et al.
Publicado: (2020)

The Emerging Role of the Double-Edged Impact of Arachidonic Acid-Derived Eicosanoids in the Neuroinflammatory Background of Depression
por: Regulska, Magdalena, et al.
Publicado: (2021)

Genetics Variants in the Epoxygenase Pathway of Arachidonic Metabolism Are Associated with Eicosanoids Levels and the Risk of Diabetic Nephropathy
por: Mota-Zamorano, Sonia, et al.
Publicado: (2021)

The Polymorphism of Drugs: New Approaches to the Synthesis of Nanostructured Polymorphs
por: Chistyakov, Dmitry, et al.
Publicado: (2020)

PDBsum more: new summaries and analyses of the known 3D structures of proteins and nucleic acids
por: Laskowski, Roman A., et al.
Publicado: (2005)

Draft Genome Sequence of Bacillus amyloliquefaciens B-1895
por: Karlyshev, Andrey V., et al.
Publicado: (2014)

Modification of a SERS-active Ag surface to promote adsorption of charged analytes: effect of Cu(2+) ions
por: Ranishenka, Bahdan V, et al.
Publicado: (2021)

Treatment of infantile neuroaxonal dystrophy with RT001: A di‐deuterated ethyl ester of linoleic acid: Report of two cases
por: Adams, Darius, et al.
Publicado: (2020)

Sensory Perception of Non‐Deuterated and Deuterated Organic Compounds
por: Salthammer, Tunga, et al.
Publicado: (2020)

Curing of Epoxy Resin DER-331 by Hexakis(4-acetamidophenoxy)cyclotriphosphazene and Properties of the Prepared Composition
por: Chistyakov, Evgeniy M., et al.
Publicado: (2019)

Curing of DER-331 Epoxy Resin with Arylaminocyclotriphosphazenes Based on o-, m-, and p-methylanilines
por: Rybyan, Artem A., et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_eap54nch2vs4t0btpeldlpc2sm