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Synthesis of Cucurbitacin B Derivatives as Potential Anti-Hepatocellular Carcinoma Agents

Cucurbitacin B shows potent activity against tumor cells, but its high toxicity limits its application in the clinic. A series of cucurbitacin B derivatives was synthesized and evaluated for their anti-hepatocellular carcinoma (HCC) activities against the HepG-2 cell line. These compounds were also...

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Detalles Bibliográficos
Autores principales:	Ge, Weizhi, Chen, Xinyi, Han, Fangzhi, Liu, Zhongquan, Wang, Tianpeng, Wang, Mengmeng, Chen, Yue, Ding, Yahui, Zhang, Quan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6321601/ https://www.ncbi.nlm.nih.gov/pubmed/30567327 http://dx.doi.org/10.3390/molecules23123345

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