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Thermodynamic Characterization of the Ca(2+)-Dependent Interaction Between SOUL and ALG-2

SOUL, a heme-binding protein-2 (HEBP-2), interacts with apoptosis-linked gene 2 protein (ALG-2) in a Ca(2+)-dependent manner. To investigate the properties of the interaction of SOUL with ALG-2, we generated several mutants of SOUL and ALG-2 and analyzed the recombinant proteins using pulldown assay...

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Detalles Bibliográficos
Autores principales: Mikasa, Taisuke, Kugo, Masami, Nishimura, Seigo, Taketani, Sigeru, Ishijima, Sumio, Sagami, Ikuko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6321638/
https://www.ncbi.nlm.nih.gov/pubmed/30501057
http://dx.doi.org/10.3390/ijms19123802