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Prevalence and development of hip and knee osteoarthritis according to American College of Rheumatology criteria in the CHECK cohort
BACKGROUND: We aimed to evaluate the prevalence of hip and knee osteoarthritis (HOA and KOA) according to American College of Rheumatology (ACR) criteria among participants with suspected early symptomatic osteoarthritis (OA) in the CHECK cohort. We also assessed whether participants not fulfilling...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6321652/ https://www.ncbi.nlm.nih.gov/pubmed/30611305 http://dx.doi.org/10.1186/s13075-018-1785-7 |
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author | Damen, Jurgen van Rijn, Rogier M. Emans, Pieter J. Hilberdink, Willem K. H. A. Wesseling, Janet Oei, Edwin H. G. Bierma-Zeinstra, Sita M. A. |
author_facet | Damen, Jurgen van Rijn, Rogier M. Emans, Pieter J. Hilberdink, Willem K. H. A. Wesseling, Janet Oei, Edwin H. G. Bierma-Zeinstra, Sita M. A. |
author_sort | Damen, Jurgen |
collection | PubMed |
description | BACKGROUND: We aimed to evaluate the prevalence of hip and knee osteoarthritis (HOA and KOA) according to American College of Rheumatology (ACR) criteria among participants with suspected early symptomatic osteoarthritis (OA) in the CHECK cohort. We also assessed whether participants not fulfilling ACR criteria at baseline develop ACR-defined OA at 2-year and/or 5-year follow up, and which baseline factors are associated with this development. METHODS: The CHECK cohort included 1002 subjects with first presentation of knee and/or hip complaints. The primary outcome was onset of HOA and/or KOA according to the ACR criteria, including the clinical classification criteria and the combined clinical and radiographic classification criteria at 2-year and/or 5-year follow up. RESULTS: Of the participants with hip complaints, 63% (n = 370) were classified as having HOA at baseline according to the ACR criteria. Of those not classified with HOA at baseline, 40% developed HOA according to the clinical or combined clinical/radiographic ACR criteria after 2 and/or 5 years. Up to 92% of participants (n = 829) with knee complaints were classified as having KOA at baseline; of those not classified with KOA at baseline, 55% developed KOA according to the clinical ACR criteria or the clinical/radiographic ACR criteria after 2 and/or 5 years. The following factors were associated with development of HOA: morning stiffness (OR 2.39; 95% CI 1.14–4.98), painful internal rotation (OR 2.53; 95% CI 1.23–5.19), hip flexion < 115° (OR 2.33; 95% CI 1.17–4.64) and erythrocyte sedimentation rate (ESR) < 20 mm/h (OR 2.94; 95% CI 1.13–7.61). No variables were associated with development of KOA at 2-year and/or 5-year follow up. CONCLUSIONS: A large proportion of persons with hip complaints not fulfilling the ACR criteria at baseline develop HOA after 2 and/or 5 years of follow up. Almost all persons with knee complaints already fulfill the clinical and/or radiographic ACR criteria for OA, and half of the persons not fulfilling criteria at baseline will do so after 5 years of follow up. Several individual ACR criteria for HOA at baseline were associated with the development of HOA at follow up. This association was not proven for KOA, probably because of the small number of subjects developing KOA in this study. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1186/s13075-018-1785-7) contains supplementary material, which is available to authorized users. |
format | Online Article Text |
id | pubmed-6321652 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-63216522019-01-09 Prevalence and development of hip and knee osteoarthritis according to American College of Rheumatology criteria in the CHECK cohort Damen, Jurgen van Rijn, Rogier M. Emans, Pieter J. Hilberdink, Willem K. H. A. Wesseling, Janet Oei, Edwin H. G. Bierma-Zeinstra, Sita M. A. Arthritis Res Ther Research BACKGROUND: We aimed to evaluate the prevalence of hip and knee osteoarthritis (HOA and KOA) according to American College of Rheumatology (ACR) criteria among participants with suspected early symptomatic osteoarthritis (OA) in the CHECK cohort. We also assessed whether participants not fulfilling ACR criteria at baseline develop ACR-defined OA at 2-year and/or 5-year follow up, and which baseline factors are associated with this development. METHODS: The CHECK cohort included 1002 subjects with first presentation of knee and/or hip complaints. The primary outcome was onset of HOA and/or KOA according to the ACR criteria, including the clinical classification criteria and the combined clinical and radiographic classification criteria at 2-year and/or 5-year follow up. RESULTS: Of the participants with hip complaints, 63% (n = 370) were classified as having HOA at baseline according to the ACR criteria. Of those not classified with HOA at baseline, 40% developed HOA according to the clinical or combined clinical/radiographic ACR criteria after 2 and/or 5 years. Up to 92% of participants (n = 829) with knee complaints were classified as having KOA at baseline; of those not classified with KOA at baseline, 55% developed KOA according to the clinical ACR criteria or the clinical/radiographic ACR criteria after 2 and/or 5 years. The following factors were associated with development of HOA: morning stiffness (OR 2.39; 95% CI 1.14–4.98), painful internal rotation (OR 2.53; 95% CI 1.23–5.19), hip flexion < 115° (OR 2.33; 95% CI 1.17–4.64) and erythrocyte sedimentation rate (ESR) < 20 mm/h (OR 2.94; 95% CI 1.13–7.61). No variables were associated with development of KOA at 2-year and/or 5-year follow up. CONCLUSIONS: A large proportion of persons with hip complaints not fulfilling the ACR criteria at baseline develop HOA after 2 and/or 5 years of follow up. Almost all persons with knee complaints already fulfill the clinical and/or radiographic ACR criteria for OA, and half of the persons not fulfilling criteria at baseline will do so after 5 years of follow up. Several individual ACR criteria for HOA at baseline were associated with the development of HOA at follow up. This association was not proven for KOA, probably because of the small number of subjects developing KOA in this study. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1186/s13075-018-1785-7) contains supplementary material, which is available to authorized users. BioMed Central 2019-01-05 2019 /pmc/articles/PMC6321652/ /pubmed/30611305 http://dx.doi.org/10.1186/s13075-018-1785-7 Text en © The Author(s). 2019 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. |
spellingShingle | Research Damen, Jurgen van Rijn, Rogier M. Emans, Pieter J. Hilberdink, Willem K. H. A. Wesseling, Janet Oei, Edwin H. G. Bierma-Zeinstra, Sita M. A. Prevalence and development of hip and knee osteoarthritis according to American College of Rheumatology criteria in the CHECK cohort |
title | Prevalence and development of hip and knee osteoarthritis according to American College of Rheumatology criteria in the CHECK cohort |
title_full | Prevalence and development of hip and knee osteoarthritis according to American College of Rheumatology criteria in the CHECK cohort |
title_fullStr | Prevalence and development of hip and knee osteoarthritis according to American College of Rheumatology criteria in the CHECK cohort |
title_full_unstemmed | Prevalence and development of hip and knee osteoarthritis according to American College of Rheumatology criteria in the CHECK cohort |
title_short | Prevalence and development of hip and knee osteoarthritis according to American College of Rheumatology criteria in the CHECK cohort |
title_sort | prevalence and development of hip and knee osteoarthritis according to american college of rheumatology criteria in the check cohort |
topic | Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6321652/ https://www.ncbi.nlm.nih.gov/pubmed/30611305 http://dx.doi.org/10.1186/s13075-018-1785-7 |
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