A prospect of cell immortalization combined with matrix microenvironmental optimization strategy for tissue engineering and regeneration

Cellular senescence is a major hurdle for primary cell-based tissue engineering and regenerative medicine. Telomere erosion, oxidative stress, the expression of oncogenes and the loss of tumor suppressor genes all may account for the cellular senescence process with the involvement of various signal...

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Detalles Bibliográficos
Autores principales: Wang, Yiming, Chen, Song, Yan, Zuoqin, Pei, Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6321683/
https://www.ncbi.nlm.nih.gov/pubmed/30627420
http://dx.doi.org/10.1186/s13578-018-0264-9

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