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Ty3 reverse transcriptase complexed with an RNA-DNA hybrid shows structural and functional asymmetry
Retrotransposons are a class of mobile genetic elements that replicate by converting their single-stranded RNA intermediate to double-stranded DNA through the combined DNA polymerase and ribonuclease H (RNase H) activities of the element-encoded reverse transcriptase (RT). However, while a wealth of...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6321743/ https://www.ncbi.nlm.nih.gov/pubmed/24608367 http://dx.doi.org/10.1038/nsmb.2785 |