Ty3 reverse transcriptase complexed with an RNA-DNA hybrid shows structural and functional asymmetry

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Retrotransposons are a class of mobile genetic elements that replicate by converting their single-stranded RNA intermediate to double-stranded DNA through the combined DNA polymerase and ribonuclease H (RNase H) activities of the element-encoded reverse transcriptase (RT). However, while a wealth of...

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Detalles Bibliográficos
Autores principales: Nowak, Elżbieta, Miller, Jennifer T., Bona, Marion K., Studnicka, Justyna, Szczepanowski, Roman H., Jurkowski, Jakub, Le Grice, Stuart F. J., Nowotny, Marcin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6321743/
https://www.ncbi.nlm.nih.gov/pubmed/24608367
http://dx.doi.org/10.1038/nsmb.2785

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